Table 1 Metabolic state and body weight of the experimental rats.

From: Dichloroacetate as a metabolic modulator of heart mitochondrial proteome under conditions of reduced oxygen utilization

Metabolic parameters and body weight

Control

DCA

DM

DM + DCA

Glucose (mmol.L−1)

6.78 ± 0.36

5.80 ± 0.21

26.3 ± 2.18**

25.2 ± 2.06**

Triacylglycerol (g.L−1)

1.40 ± 0.22

1.33 ± 0.18

4.92 ± 0.43**

4.85 ± 0.38**

Cholesterol (mmol.L−1)

1.85 ± 0.26

1.79 ± 0.19

2.54 ± 0.30*

2.52 ± 0.24*

Insulin (ng.mL−1)

1.11 ± 0.18

1.13 ± 0.20

0.42 ± 0.10**

0.46 ± 0.14**

Body weight (g)

360 ± 12

368 ± 14

319 ± 19*

307 ± 18**

  1. All values are presented as the mean ± standard error of the mean (SEM). Control—untreated control group; DCA—control group treated with dichloroacetate; DM—diabetic group; DM + DCA—diabetic group treated with dichloroacetate *p < 0.05, **p < 0.01 compared to Control.
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