Figure 6
Advanced disease characterization in the left dentary of Tyrannosaurus rex using DECT-based fluorine quantification. Conventional CT reconstruction (a) and DECT-based fluorine map (b) of the left dentary in coronal plane at the level of the focal exophytic mass showing significant fluorine accumulation in areas of reduced bone density (arrowheads). DECT also revealed increased fluorine accumulation at the base of the tooth root and a connecting fluorine deposit in a fistula-like structure in the sagittal plane (c; arrow). Red indicates high concentrations of fluorine measured in Hounsfield units (color bar in the upper right corner) whereby the signals on the surface are due to beam hardening artefacts. The Whisker plots show that fluorine content in the exophytic mass was higher than that of the surrounding healthy bone tissue (p < 0.001), while the calcium content did not show any differences. The white dotted line indicates the cross-sectional plane of images (a) and (b).
