Table 3 Demographic and clinical characteristics at baseline (fasting state) for atherosclerotic plaque versus no atherosclerotic plaque groups stratified by gender.
Variable | Plaque 0 | Plaque > 0 | P value for plaque category | P value for gender distribution | P value for gender* variable interaction on plaque category | |||
|---|---|---|---|---|---|---|---|---|
Males (n = 30) | Females (n = 33) | Males (n = 25) | Females (n = 13) | |||||
BMI (kg/m2) | 23.85 ± 2.80 | 23.26 ± 3.03 | 23.68 ± 2.89 | 22.98 ± 2.68 | 0.8630 | 0.3081 | 0.9331 | |
Weight (kg) | 70.21 ± 9.15 | 60.07 ± 8.25 | 70.74 ± 10.28 | 56.48 ± 5.77 | 0.6547 | < .0001 | 0.1836 | |
Glucose (mmol/L) | 5.06 ± 0.39 | 5.0 ± 0.34 | 5.17 ± 0.40 | 4.88 ± 0.42 | 0.5818 | 0.0624 | 0.1410 | |
Insulin (uU/mL ) | 7.47 ± 4.86 | 8.15 ± 4.79 | 9.19 ± 6.37 | 7.62 ± 4.66 | 0.4426 | 0.8132 | 0.3573 | |
C-Peptide (ng/ml) | 1.88 ± 0.79 | 2.02 ± 0.81 | 2.17 ± 0.90 | 1.84 ± 0.66 | 0.5379 | 0.7994 | 0.1900 | |
LDL-C (mmol/l) | 3.31 ± 0.74 | 3.13 ± 0.74 | 3.41 ± 0.75 | 3.58 ± 0.61 | 0.0942 | 0.4934 | 0.2667 | |
HDL-C (mmol/L) | 1.48 ± 0.28 | 1.62 ± 0.26 | 1.37 ± 0.31 | 1.80 ± 0.42 | 0.6128 | 0.0002 | 0.0271 | |
Triacylglycerol (mmol/L) | 1.13 ± 0.70 | 0.91 ± 0.43 | 1.31 ± 0.64 | 0.79 ± 0.34 | 0.3386 | 0.0028 | 0.2279 | |
Cholesterol (mmol/l) | 5.30 ± 0.86 | 5.15 ± 0.89 | 5.37 ± 0.87 | 5.73 ± 0.72 | 0.1318 | 0.9343 | 0.1907 | |
age | 46.47 ± 4.15 | 47.30 ± 4.64 | 48.80 ± 3.59 | 49.23 ± 4.13 | 0.0188 | 0.7084 | 0.6239 | |
Framingham score | 4.83 ± 2.57 | 5.42 ± 2.89 | 6.44 ± 2.20 | 6.62 ± 3.10 | 0.0144 | 0.7188 | 0.4227 | |
HOMA-IR | 1.84 ± 1.31 | 1.94 ± 1.20 | 2.30 ± 1.71 | 1.75 ± 1.08 | 0.4333 | 0.5615 | 0.3105 | |
HOMA-β | 78.66 ± 48.77 | 91.98 ± 50.74 | 91.19 ± 61.31 | 97.41 ± 64.15 | 0.4941 | 0.4018 | 0.7510 | |
Adiponectin (pg/mL) | 5,454,728 ± 2,361,782 | 6,099,140 ± 2,424,829 | 4,518,684 ± 1,743,636 | 5,953,585 ± 1,547,828 | 0.0853 | 0.0193 | 0.3452 | |
TNFα (pg/mL) | 23.50 ± 16.96 | 13.66 ± 8.02 | 16.77 ± 13.56 | 10.54 ± 3.38 | 0.1688 | 0.0018 | 0.3042 | |
PAI-1 (pg/mL) | 27,463.6 ± 11,895.7 | 21,808.6 ± 9059.3 | 31,909.4 ± 10,408.2 | 27,134.9 ± 8870.3 | 0.0089 | 0.0039 | 0.4767 | |
Leptin (pg/mL) | 2147.8 ± 1643.6 | 9630.3 ± 6828.8 | 2804.4 ± 2839.2 | 6345.4 ± 3305.9 | 0.0363 | < .0001 | 0.0919 | |