Table 1 The interaction energies between NPs and vesicles and energy barriers heights between vesicles and cell membranes for 64 organically-coated gold NPs.
No | NPs | Cells | ΔGnp/v kJ/mol | ΔG‡v/m kJ/mol | No | NPs | Cells | ΔGnp/v kJ/mol | ΔG‡v/m kJ/mol |
|---|---|---|---|---|---|---|---|---|---|
1 | C1(methoxy) | RAW 264.7 | 779 | 1171 | 33 | C12B(2-butyloctyl) | Hela | 453 | 1270 |
2 | C6S(hexyl) | RAW 264.7 | 571 | 1185 | 34 | C12C(cyclododecyl) | Hela | 436 | 1194 |
3 | C6B-2(3,3-dimethylbutyl) | RAW 264.7 | 579 | 1199 | 35 | C12A-1(5-naphthybutyl) | Hela | 505 | 1250 |
4 | C6C(cyclohexyl) | RAW 264.7 | 577 | 1165 | 36 | C12A-2(7-phenylheptyl) | Hela | 458 | 1199 |
5 | C6E-1(5-hexenyl) | RAW 264.7 | 570 | 1165 | 37 | Citrate | U937 | 675 | 667 |
6 | C6E-2(2-hexenyl) | RAW 264.7 | 607 | 1237 | 38 | Citrate | U937 | 1259 | 1243 |
7 | C6A(phenyl) | RAW 264.7 | 682 | 1302 | 39 | Citrate | U937 | 2132 | 2105 |
8 | C12S(dodecyl) | RAW 264.7 | 455 | 1274 | 40 | Cysteamine | U937 | 346 | 624 |
9 | C12B(2-butyloctyl) | RAW 264.7 | 453 | 1270 | 41 | Cysteamine | U937 | 744 | 1343 |
10 | C12C(cyclododecyl) | RAW 264.7 | 436 | 1194 | 42 | Cysteamine | U937 | 1225 | 2212 |
11 | C12A-1(5-naphthybutyl) | RAW 264.7 | 505 | 1250 | 43 | L-cysteine | U937 | 591 | 753 |
12 | C12A-2(7-phenylheptyl) | RAW 264.7 | 458 | 1199 | 44 | L-cysteine | U937 | 990 | 1260 |
13 | C1(methoxy) | C166 | 779 | 1171 | 45 | L-cysteine | U937 | 1776 | 2260 |
14 | C6S(hexyl) | C166 | 571 | 1185 | 46 | PEG | U937 | 1266 | 1177 |
15 | C6B-2(3,3-dimethylbutyl) | C166 | 579 | 1199 | 47 | PEG | U937 | 1789 | 1663 |
16 | C6C(cyclohexyl) | C166 | 577 | 1165 | 48 | PEG | U937 | 2746 | 2552 |
17 | C6E-1(5-hexenyl) | C166 | 570 | 1165 | 49 | Transferrin | STO | 477 | 648 |
18 | C6E-2(2-hexenyl) | C166 | 607 | 1237 | 50 | Transferrin | STO | 1022 | 1388 |
19 | C6A(phenyl) | C166 | 682 | 1302 | 51 | Transferrin | STO | 1703 | 2314 |
20 | C12S(dodecyl) | C166 | 455 | 1274 | 52 | Transferrin | STO | 2520 | 3425 |
21 | C12B(2-butyloctyl) | C166 | 453 | 1270 | 53 | Transferrin | STO | 3406 | 4628 |
22 | C12C(cyclododecyl) | C166 | 436 | 1194 | 54 | Transferrin | SNB19 | 477 | 648 |
23 | C12A-1(5-naphthybutyl) | C166 | 505 | 1250 | 55 | Transferrin | SNB19 | 1022 | 1388 |
24 | C12A-2(7-phenylheptyl) | C166 | 458 | 1199 | 56 | Transferrin | SNB19 | 1703 | 2314 |
25 | C1(methoxy) | Hela | 779 | 1171 | 57 | Transferrin | SNB19 | 2520 | 3425 |
26 | C6S(hexyl) | Hela | 571 | 1185 | 58 | Transferrin | SNB19 | 3406 | 4628 |
27 | C6B-2(3,3-dimethylbutyl) | Hela | 579 | 1199 | 59 | Transferrin | Hela | 477 | 648 |
28 | C6C(cyclohexyl) | Hela | 577 | 1165 | 60 | Transferrin | Hela | 1022 | 1388 |
29 | C6E-1(5-hexenyl) | Hela | 570 | 1165 | 61 | Transferrin | Hela | 1703 | 2314 |
30 | C6E-2(2-hexenyl) | Hela | 607 | 1237 | 62 | Transferrin | Hela | 2520 | 3425 |
31 | C6A(phenyl) | Hela | 682 | 1302 | 63 | Transferrin | Hela | 3406 | 4628 |
32 | C12S(dodecyl) | Hela | 455 | 1274 | 64 | D-penicillamine | Hela | 248 | 370 |
