Table 3 Estimated unadjusted and adjusted odds ratios for stroke, stroke risk factors in women, as predicted by duration (years) of husband opiate smoking after marriage.

From: Cross-sectional study of passive opiate smoking in relation to stroke and some of stroke attributable risk factors in women

 

Unadjusted model

Final adjusted model

 

OR (95% CI)

p-value

OR (95% CI)

p-value

Husband opiate smoking

Stroke (total n = 1525)

p-Trend = 0.02

Not passive opiate (n = 1301)

Reference

   

1–10 years passive opiate (n = 130)

3.41 (1.08–10.73)

0.03

2.88 (0.86–9.62)

0.09a

> 10 years passive opiate (n = 94)

4.77 (1.51–15.10)

 < 0.01

4.17 (1.27–13.76)

0.02a

Chol > 200 mg/dl (total n = 1541)

   

p-Trend = 0.05

Not passive opiate (n = 1315)

Reference

   

1–10 years passive opiate (n = 131)

0.93(0.65–1.33)

0.69

0.84(0.58–1.22)

0.37b

 > 10 years passive opiate (n = 95)

1.83(1.20–2.81)

 < 0.01

1.55(1–2.40)

0.05b

FBS > 125 (total n = 1541)

   

p-Trend = 0.33

Not passive opiate (n = 1315)

Reference

   

1–10 years passive opiate (n = 131)

2.02 (1.31–3.11)

 < 0.01

1.82 (1.14–2.92)

0.01c

 > 10 years passive opiate (n = 95)

1.85 (1.11- 3.08)

0.02

1.31 (0.76 2.26)

0.33c

Hypertension (total n = 1541)

   

p-Trend = 0.25

not passive opiate (n = 1315)

Reference

   

1–10 years passive opiate (n = 131)

1.11(0.73–1.69)

0.62

0.84(0.52–1.37)

0.49d

 > 10 years passive opiate (n = 95)

1.83(1.18–2.85)

 < 0.01

1.34(0.81–2.22)

0.25d

LDL > 100 mg/dl (total n = 1541)

p-Trend = 0.01

Not passive opiate (n = 1315)

Reference

   

1–10 years passive opiate (n = 131)

1.14 (0.79–1.65)

0.478

1.12 (0.77- 1.64)

0.77e

 > 10 years passive opiate (n = 95)

1.98 (1.24–3.16)

 < 0.01

1.88 (1.15 -3.05)

0.01e

Overweight/obesity (BMI > 25) (total n = 1541)

   

p-Trend = 0.54

Not passive opiate (n = 1315)

Reference

   

1–10 years passive opiate (n = 131)

1.17(0.82–1.68)

0.39

1.02(0.71–1.48)

0.90f

 > 10 years passive opiate (n = 95)

1.05(0.69–1.60)

0.81

0.87(0.57–1.34)

0.54f

TG ≥ 150 mg/dl (total n = 1541)

   

p-Trend = 0.97

Not passive opiate (n = 1315)

Reference

   

1–10 years passive opiate (n = 131)

1.22(0.85–1.74)

0.28

1.11(0.76–1.61)

0.59g

> 10 years passive opiate (n = 95)

1.22(0.80–1.85)

0.35

1.01(0.65–1.55)

0.98g

Total diabetes (total n = 1541)

   

p-Trend = 0.64

Not passive opiate (n = 1315)

Reference

   

1–10 years passive opiate (n = 131)

1.61(1.08–2.41)

0.02

1.38(0.88–2.15)

0.16g

> 10 years passive opiate (n = 95)

1.65(1.04–2.61)

0.03

1.13(0.68–1.86)

0.65g

Chronic headaches (total n = 1525)

p-Trend = 0.04

Not passive opiate (n = 1301)

Reference

   

1–10 years passive opiate (n = 130)

1.10 (0.57–2.10)

0.78

1.02 (0.53–1.97)

0.95h

 > 10 years passive opiate (n = 94)

2.08 (1.14–3.80)

0.01

1.89 (1.02–3.50)

0.04h

  1. Estimated unadjusted and adjusted odds ratios for stroke, high Chol, FBS, hypertension, LDL, overweight/obesity, high Tg, diabetes and chronic headache in women, as predicted by husband opiate smoking.
  2. Significant values are in bold.
  3. OR odds ratio, CI confidence interval, LDL low density lipoprotein, Chol cholesterol, TG triglyceride.
  4. aAdjusted for age, education years, BMI, stage 2 hypertension, diabetes, MET and family history of stroke.
  5. bAdjusted for age, education years, BMI, stage 2 hypertension and family history of hypertension.
  6. cAdjusted for age, education years, BMI, MET and family history of diabetes.
  7. dAdjusted for age, education years, BMI, MET and family history of hypertension.
  8. eAdjusted for age, education years, BMI, stage 2 hypertension, diabetes and family history of hypertension.
  9. fAdjusted for age, education years, MET and diabetes.
  10. gAdjusted for age, education years, BMI, MET and family history of diabetes.
  11. hAdjusted for age, education years, stage 2 hypertension and family history of recurrent chronic headache.
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