Table 1 Demographic and clinical characteristics of patients with NM-GBA.
Characteristic | Item | Overall | Training cohort | Validation cohort | P value |
|---|---|---|---|---|---|
Total, n | 1035 | 727 | 308 | ||
Sex, n (%) | Female | 721 (69.7%) | 515 (70.8%) | 206 (66.9%) | 0.233 |
Male | 314 (30.3%) | 212 (29.2%) | 102 (33.1%) | ||
Race, n (%) | White | 791 (76.4%) | 556 (76.5%) | 235 (76.3%) | 0.301 |
Black | 112 (10.8%) | 84 (11.6%) | 28 (9.1%) | ||
Other | 132 (12.8%) | 87 (12%) | 45 (14.6%) | ||
Grade, n (%) | G1 | 153 (14.8%) | 110 (15.1%) | 43 (14%) | 0.805 |
G2 | 493 (47.6%) | 339 (46.6%) | 154 (50%) | ||
G3 | 375 (36.2%) | 268 (36.9%) | 107 (34.7%) | ||
G4 | 14 (1.4%) | 10 (1.4%) | 4 (1.3%) | ||
T, n (%) | T1 | 118 (11.4%) | 92 (12.7%) | 26 (8.4%) | 0.162 |
T2 | 533 (51.5%) | 374 (51.4%) | 159 (51.6%) | ||
T3 | 352 (34%) | 237 (32.6%) | 115 (37.3%) | ||
T4 | 32 (3.1%) | 24 (3.3%) | 8 (2.6%) | ||
N, n (%) | N0 | 560 (54.1%) | 393 (54.1%) | 167 (54.2%) | 0.816 |
N1 | 437 (42.2%) | 309 (42.5%) | 128 (41.6%) | ||
N2 | 38 (3.7%) | 25 (3.4%) | 13 (4.2%) | ||
Stage, n (%) | Stage I | 107 (10.3%) | 81 (11.1%) | 26 (8.4%) | 0.596 |
Stage II | 295 (28.5%) | 207 (28.5%) | 88 (28.6%) | ||
Stage III | 567 (54.8%) | 392 (53.9%) | 175 (56.8%) | ||
Stage IV | 66 (6.4%) | 47 (6.5%) | 19 (6.2%) | ||
Radiation, n (%) | None | 765 (73.9%) | 539 (74.1%) | 226 (73.4%) | 0.858 |
Yes | 270 (26.1%) | 188 (25.9%) | 82 (26.6%) | ||
Chemotherapy, n (%) | None | 613 (59.2%) | 438 (60.2%) | 175 (56.8%) | 0.338 |
Yes | 422 (40.8%) | 289 (39.8%) | 133 (43.2%) | ||
Marital, n (%) | Married | 564 (54.5%) | 397 (54.6%) | 167 (54.2%) | 0.211 |
Single | 140 (13.5%) | 92 (12.7%) | 48 (15.6%) | ||
Separated | 112 (10.8%) | 87 (12%) | 25 (8.1%) | ||
Widowed | 219 (21.2%) | 151 (20.8%) | 68 (22.1%) | ||
NRLN, median (IQR) | 2 (1, 5) | 2 (1, 4) | 2 (1, 5) | 0.255 | |
NPLN, median (IQR) | 0 (0, 1) | 0 (0, 1) | 0 (0, 1) | 0.880 | |
LNR, median (IQR) | 0 (0, 0.8) | 0 (0, 1) | 0 (0, 0.67) | 0.722 | |
LODDS, median (IQR) | -1.32 (-1.613, 0.591) | -1.32 (-1.61, 1.32) | -1.32 (-1.79, 0.29) | 0.490 | |
Size (mm), median (IQR) | 30 (20, 42) | 30 (20, 40) | 30 (20, 45) | 0.742 | |
Age (years), median (IQR) | 68 (60, 77) | 69 (60, 78) | 68 (59.75, 76) | 0.382 | |
Survival, median (IQR) | 28 (11, 56) | 28 (11, 56) | 30 (11, 56.25) | 0.984 |
