Table 4 Comparison of major studies that developed predictive nomograms included LODDS in GBC.

From: A novel nomogram based on log odds of positive lymph nodes to predict survival for non-metastatic gallbladder adenocarcinoma after surgery

References

Type of study, sample size

Purpose of study

Parameters included

C-index (95% CI) of nomogram in validation set

Xiao et al., 201923

SEER database analysis, n = 1321

To establish a prognostic model including LODDS of GBC patients after resection

Age, grade, size, LODDS, AJCC 8th edition T, AJCC 8th edition M

0.752 (0.720–0.768)

Li et al., 202015

SEER database analysis, n = 1612

To establish a prognostic model including LODDS of GBA patients over 45 years after resection

Age, grade, size, LODDS, AJCC 8th edition T, AJCC 8th edition M, marital status

0.740 (0.721–0.759)

Yuan et al., 202114

SEER database analysis and single-center study, n = 856

To establish a prognostic model including LODDS of patients with T3 and T4 GBC after resection

Age, grade, LODDS, AJCC 8th edition M, chemotherapy, radiotherapy

0.719 (0.707–0.713)

Current study

SEER database analysis, n = 1035

To establish a prognostic model including LODDS of patients with non-metastatic GBA after resection

Age, grade, size, sex, LODDS, AJCC 8th edition stage, chemotherapy

0.746 (0.717–0.775)

  1. LODDS log odds of positive lymph nodes, GBC gallbladder cancer, GBA gallbladder adenocarcinoma, CI confidence interval, SEER surveillance, epidemiology and end results.
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