Table 3 Effect of the retinal layer thickness to the retinopathy of prematurity and the laser treatment.

From: Effect of foveal morphology on visual acuity in 4–6-year-old children with retinopathy of prematurity: a J-CREST study

 

ROP (Treated ROP +  Regressed ROP) (n = 74)

No ROP (Control) (n = 30)

Pa

Laser treatment (Treated ROP) (n = 41)

No Laser treatment (Regressed ROP + Control) (n = 63)

Pb

Foveal thickness [µm]

242.0

243.3

0.90

252.0

236.1

0.005

Difference(95%CI)

234.5 to 249.5

227.2 to 259.5

 

244.3 to 260.0

230.1 to 242.0

 

Foveal depression [µm]

78.2

95.0

0.26

78.1

86.3

0.27

Difference(95%CI)

68.1 to 88.3

73.3 to 113.7

 

67.6 to 88.6

78.3 to 94.3

 

ONL thickness [µm]

107.9

104.7

0.66

109.8

105.2

0.22

Difference(95%CI)

102.8 to 113.0

93.8 to 115.6

 

104.5 to 111.1

101.1 to 109.2

 

IS Thickness [µm]

45.1

38.2

0.05

45.4

41.6

0.03

Difference(95%CI)

42.7 to 47.5

33.1 to 43.3

 

43.0 to 47.9

39.7 to 43.4

 

OS Thickness [µm]

42.7

40.0

0.19

43.1

41.2

0.08

Difference(95%CI)

41.3 to 44.1

37.0 to 43.0

 

41.6 to 44.1

40.1 to 42.3

 

IRL Thickness [µm]

8.6

0

0.01

13.4

4.8

0.01

Difference(95%CI)

5.9 to 11.3

  

8.9 to 17.9

0.9 to 8.7

 
  1. Data are expressed as adjusted mean based on analysis of covariance (ANCOVA).
  2. P value aANCOVA adjusted for gestational age and laser treatment bANCOVA adjusted for gestational age and ROP.
  3. ROP: retinopathy of prematurity, CI, confidence interval, ONL: outer nuclear layer, IS: inner segment, OS: outer segment, IRL: inner retinal layer.