Table 4 KIR genotype frequencies among patients with lung cancer and healthy controls.

From: KIR-HLA gene diversities and susceptibility to lung cancer

KIR

Healthy controls

Lung cancer

Comparisons

Lung cancer

NSCLC

SCLC

Lung cancer versus HC

NSCLC versus HC

SCLC versus HC

n = 448

n = 232

n = 179

n = 53

p value

OR (95% CI)

p value

OR (95% CI)

p value

OR (95% CI)

%F (N+)

%F (N+)

%F (N+)

%F (N+)

KIR genotypes

AA

25.7 (115)

19.4 (45)

19.5 (35)

16.9 (9)

      

Bx

74.3 (333)

80.6 (187)

80.4 (144)

83.1 (44)

      

CxT4

22.7 (102)

17.6 (41)

18.4 (33)

15.0 (8)

      

C4Tx

23.4 (105)

28.4 (66)

29.6 (53)

24.5 (13)

      

C4T4

12.7 (57)

9.5 (22)

8.37 (15)

13.2 (7)

      

CxTx

15.4 (69)

25.0 (58)

24.0 (43)

30.2 (16)

0.0035

1.83 (1.23–2.71)

0.015

1.74 (1.13–2.66)

0.011

2.37 (1.25–4.5)

C4 Linkage groups

36.2 (162)

37.9 (88)

37.9 (68)

37.7 (20)

      

T4 Linkage groups

35.4 (159)

27.1 (63)

26.8 (48)

28.3 (15)

0.03

0.67 (0.47–0.97)

0.0039

0.66 (0.45–0.97)

  
  1. N + number of individuals positive for the gene, n number of individuals tested for the gene, HC healthy control, OR odds ratio, CI confidence interval. p < 0.05: statistically significant; based on two-tailed Fisher’s exact test.