Figure 4

Reconstructed 3-dimensional geometry in a patient with AS who received TAVR using computed tomography, schematic diagram of LPM pressure boundary conditions and FSI. (a) CT views (coronal, sagittal and axial) of the ascending aorta, coronary branches, sinus of Valsalva and aortic valve for pre-TAVR (left column) and post-TAVR (middle and right column) as well as the segmentation process and geometry reconstruction; (b) computational domain and boundary condition. FSI simulations performed during diastole. Patient-specific LPM simulating the coronary perfusion pressure (ascending aorta pressure—LV diastolic pressure). This data was obtained from patient-specific imaged based lumped parameter model (Fig. 1).