Figure 5

Comparison and correlation of MIF and IL-18 levels in serum and BAL of sarcoidosis patients. Boxplot depicts the differences of median and interquartile range of MIF. BAL samples displayed significant higher levels of MIF as compared to serum values using paired t-test (p = 2.8e−4) (A). Boxplot depicts the differences of median and interquartile range of IL-18 in serum and BAL samples. IL-18 level was significantly higher (p = 1.6e−15) in serum as compared to BAL (B). A correlation scatterplot of BAL IL-18 and BAL MIF values. There was a significant negative correlation between the levels of BAL IL-18 and BAL MIF (r = − 0.35, p = 0.02) (C). Correlation scatter plot displayed significant positive correlation between BAL MIF and BAL IFN-γ (r = − 0.395, p = 0.003) (D). p value < 0.05 was considered to be significant.