Figure 6 | Scientific Reports

Figure 6

From: Congenital adiponectin deficiency mitigates high-fat-diet-induced obesity in gonadally intact male and female, but not in ovariectomized mice

Figure 6The alternative text for this image may have been generated using AI.

Adiponectin deficiency limits adipose tissue inflammation in gonadally intact males and females, but not ovariectomized females. After 16 weeks of HFD, adipose tissue inflammation was assessed via qRT-PCR in (A) F WT and APN−/− mice (n = 15–16), (B) M WT and APN−/− mice (n = 15–16), and (C) OVX WT and APN−/− mice (n = 15–16), as well as (D) western blot analysis of p-JNK activation in M WT and APN−/− mice (n = 15). Data is presented as mean ± SE. *Signifies statistically significant differences (P < 0.05).

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