Table 2 Univariate and multivariate logistic regression analyses of cytokines significantly associated with HBV reactivation.

From: Serum IL-1β predicts de novo hepatitis B virus reactivation during direct-acting antiviral therapy for hepatitis C, not during anti-cancer/immunosuppressive therapy

 

Reactivation

Non-reactivation

Univariate analysis

Multivariate analysis

Odds ratio

Number

11

35

   

IL-1α (pg/mL)

 < 10.22, 10.22 ≤ 

9/2

9/26

*0.001

0.202

 

IL-1β (pg/mL)

 < 0.18, 0.18 ≤ 

9/2

3/32

* < 0.001

*0.001

47.6 (6.94–333.3)

TNFα (pg/mL)

 < 4.813, 4.813 ≤ 

9/2

13/22

*0.01

0.111

 
  1. HBV hepatitis B virus, IL interleukin, TNF tumor necrosis factor.
  2. *Statistically significant difference, P < 0.05.
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