Figure 2 | Scientific Reports

Figure 2

From: Effects of high fat diet-induced obesity on pathophysiology, immune cells, and therapeutic efficacy in systemic lupus erythematosus

Figure 2

Intraperitoneal glucose tolerance test and body composition. (A) Intraperitoneal glucose tolerance test at 36 weeks of age (all mice in the first experiment, CN: n = 11, CP: n = 9, HN: n = 14, HP: n = 9). (B) Body weight (total mass, g), total weight of fat (g), lean mass (g), percentage of fat, and percentage of lean mass measured by dual-energy X-ray absorptiometry at 42 weeks of age (n = 6 per group). The data from (A) were compared using the Kruskal–Wallis test followed by the Mann–Whitney U test. The data from (B) were compared among groups using one-way analysis of variance (ANOVA) followed by post hoc Tukey's multiple-comparison tests (n = 6 per group). A P-value < 0.05 was considered statistically significant. CN chow diet and non-treatment control (saline, 200 μl/day), CP chow diet and methylprednisolone treatment (5 mg/kg/day), HN high fat-diet and non-treatment control (saline, 200 μl/day), HP high fat-diet and methylprednisolone treatment (5 mg/kg/day).

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