Figure 3

Voxel-wise statistical maps using DTI and NODDI derived parametric maps. Clusters depicted in false color indicate regions where PME (n = 15) animals exhibited significantly higher values compared to PSE (n = 15). The results were family-wise error corrected for multiple comparisons (p < 0.05). Variation in color maps highlight the degree of significance. The results are overlayed on a study specific B0 template for better visualization. FA: fractional anisotropy, MD: mean diffusivity, AD: axial diffusivity, RD: radial diffusivity, ODI: orientation dispersion index and DAI, dispersion anisotropy index. L and R indicate anatomical orientation: Left–Right. S and I indicate anatomical orientation: superior–inferior.