Table 4 Partial correlation of macular VD measurements with MMSE scores.

From: Differences in macular vessel density in the superficial plexus across cognitive impairment: the NORFACE cohort

Diagnostic groups

Variable

r

Significance

Whole sample (n = 672)

VD nasal

0.01

0.97

VD superior

0.04

0.27

VD temporal

− 0.03

0.39

VD inferior

− 0.01

0.83

CU (n = 128)

VD nasal

0.03

0.71

VD superior

0.05

0.62

VD temporal

0.04

0.67

VD inferior

− 0.07

0.43

MCI-AD (n = 120)

VD nasal

− 0.17

0.07

VD superior

0.10

0.31

VD temporal

− 0.09

0.92

VD inferior

0.16

0.09

MCI-Va (n = 111)

VD nasal

0.10

0.33

VD superior

0.14

0.15

VD temporal

− 0.12

0.23

VD inferior

− 0.13

0.20

ADD (n = 257)

VD nasal

− 0.06

0.35

VD superior

0.07

0.27

VD temporal

0.03

0.66

VD inferior

− 0.04

0.52

VaD (n = 56)

VD nasal

− 0.06

0.69

VD superior

− 0.01

0.99

VD temporal

0.06

0.68

VD inferior

0.11

0.46

  1. The model included the following adjusting factors: age, sex, years of education, hypertension, diabetes mellitus and stroke.
  2. ADD = probable Alzheimer´s disease dementia; CU = cognitively unimpaired; MCI-AD = mild cognitive impairment due to Alzheimer´s disease; MCI-Va = mild cognitive impairment due to cerebrovascular pathology; VaD = vascular dementia; VD = vessel density.
  3. Significance was set up at p < 0.05.
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