Table 1 Demographic characteristics of patients with first-ever acute optic neuritis (ON) stratified by etiology.

From: Obesity is associated with myelin oligodendrocyte glycoprotein antibody-associated disease in acute optic neuritis

 

MOGAD

n = 44

AQP4-IgG+ NMOSD

n = 49

MS

n = 90

p-value

Age at ON onset (years), mean (SD)/median [IQR]

44.48 (14.20)/45.50 [32.50, 54.00]

41.84 (16.92)/38.00 [26.00, 54.00]

34.54 (10.72)/32.00 [25.25, 42.00]

 < 0.001

Female sex, n (%)

27 (61%)

42 (86%)

27 (52%)

 < 0.001

BMI (kg/m2), mean (SD)

31.60 (7.15)

24.69 (5.31)

26.89 (6.18)

 < 0.001

Overweight, n (%)

12 (27.27%)

8 (16.33%)

23 (25.56%)

0.387

Obese, n (%)

23 (52.27%)

8 (16.33%)

23 (25.56%)

 < 0.001

  1. MOGAD, myelin oligodendrocyte glycoprotein antibody-associated disease; AQP4-IgG+ NMOSD, aquaporin 4-IgG positive neuromyelitis optica spectrum disorder; MS, multiple sclerosis; ON, optic neuritis; SD, standard deviation; IQR, interquartile range; N, sample size; BMI, body mass index.
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