Figure 3
C23 PACE4 peptide inhibitor blocks JHU-LNCaP-SM cells proliferation and clonogenic potential. (A) Dose–response MTT proliferation assays in LNCaP and JHU-LNCaP-SM with IC50 values. (B) Colony formation assays on LNCaP and JHU-LNCaP-SM cell lines after C23 treatment (50 mM) with representative images of colonies after 14 days. Data are means ± SEM (n = 3–6). ****p < 0.0001 from a Student t-test.
