Figure 3 | Scientific Reports

Figure 3

From: Overcoming the non-kinetic activity of EGFR1 using multi-functionalized mesoporous silica nanocarrier for in vitro delivery of siRNA

Figure 3

Gel electrophoresis retardation assay of (A) siRNA@[FA-PEGylated/PEI@GuIL@KIT-6] complex with different proportions (Lane 1): Marker (50 bp), (Lane 2): siRNA, (Lane 3): (1:1), (Lane 4): (1:2), (Lane 5): (1:6), (Lane 6): (1:12), (Lane 7): (1:25), (Lane 8): (1:35), (Lane 9): (1:50). All proportions are according to (siRNA: [FA-PEGylated/PEI@GuIL@KIT-6]). (B) siRNA@[FA-PEGylated/PEI@GuIL@KIT-6] with various pore sizes. (Lane 1): Ladder (50 bp), (Lane 2): Nanocarrier MSNp = 2.5, (Lane 3): Nanocarrier MSNp = 3.5, (Lane 4): Nanocarrier MSNp = 6.5 and (Lane 5): Nanocarrier MSNp = 12.

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