Figure 2 | Scientific Reports

Figure 2

From: Massive expansion of multiple clones in the mouse hematopoietic system long after whole-body X-irradiation

Figure 2

Clonal cell percentages in BM cells of irradiated mice. Cell percentages were estimated by doubling the VAFs of CH-associated mutations (N = 70, values are shown in Supplementary Table S1) in the BM because a somatic mutation normally occurs in a chromosome of a diploid cell. A VAF of 0.1 is equivalent to 20% of the cells. Multisite mutations are clustered SNVs and insertions/deletions. BM, bone marrow; CH, clonal hematopoiesis; SNV, single-nucleotide variant; VAF, variant allele frequency.

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