Table 1 Number of recurrent somatic mutations detected in 3 Gy-irradiated and non-irradiated mice.
Mouse | Age (months) | Number of recurrent mutations with VAF > 0.02 (with VAF > 0.1) | Tumors found at autopsy | ||
|---|---|---|---|---|---|
Mosaica not CH | CH-associated | ||||
Mosaica | Non-mosaic | ||||
Irradiated | |||||
11 | 19.5 | 1 (1) | 0 | 2 (1) | Liver, stomach |
12 | 19.5 | 0 | 2 (2) | 5 (5) | Liver |
21 | 19.1 | 1 (0) | 0 | 2 (0) | Liver |
22 | 19.1 | 0 | 0 | 5 (4) | |
23 | 19.1 | 1 (1) | 0 | 0 | Liver |
31 | 19.1 | 0 | 0 | 3 (0) | Liver |
32 | 19.1 | 1 (1) | 0 | 5 (4) | |
33 | 19.1 | 0 | 1 (1) | 2 (2) | |
85 | 16 | 0 | 0 | 10 (3) | |
91 | 14.7 | 0 | 0 | 8 (1) | |
92 | 14.7 | 0 | 1 (1) | 15 (9) | |
94 | 14.7 | 0 | 1 (1) | 8 (2) | |
Mean | 17.8 | 0.3 | 0.4 | 5.4 | |
Non-irradiated | |||||
51 | 19.1 | 1 (1) | 0 | 0 | |
52 | 19.1 | 0 | 0 | 0 | |
53 | 19.4 | 1 (1) | 0 | 0 | Liver |
61 | 19.2 | 0 | 0 | 0 | |
71 | 17.2 | 3 (3) | 0 | 0 | |
73 | 18.5 | 0 | 0 | 0 | |
Mean | 18.8 | 0.8 | 0 | 0 | |
Total | 9 (8) | 5 (5) | 65 (31) | ||
