Table 4 Univariate and multivariate analyses showing the association of clinicopathological characteristics and LCR with the occurrence of postoperative complications.

From: Clinical impact of lymphocyte/C-reactive protein ratio on postoperative outcomes in patients with rectal cancer who underwent curative resection

Variables

Univariate

Multivariate

Complication

No complication

P value

OR

95%CI

P value

Age (years)

≤ 69

28

95

    

> 70

24

55

    

Sex

Male

38

83

 

2.21

1.07–4.57

0.031*

Female

14

67

0.033*

   

BMI (kg/m2)

≤ 25

7

36

    

> 25

45

114

0.110

   

Location

High

17

81

    

Low

35

69

0.008*

2.44

1.23–4.88

0.011*

Operative approach

Open

4

18

    

Laparoscopy

48

132

0.452

   

CEA (ng/mL)

≤ 5

33

99

    

> 5

19

51

0.740

   

Preoperative treatment

None

38

129

    

nCRT

12

17

    

NAC

2

4

0.097

   

Operation time (minutes)

≤ 300

22

79

    

> 300

30

71

0.198

   

Blood loss (mL)

≤ 100

33

114

    

> 100

16

34

0.177

   

pT classification

pT0–2

49

145

    

pT3–4

3

5

0.872

   

pN classification

Positive

16

40

    

Negative

36

110

0.569

   

LCR

> 12,600

34

130

    

≤ 12,600

18

20

< 0.001*

3.51

1.63–7.58

0.001*

  1. CI confidence interval, BMI body mass index, CEA carcinoembryonic antigen, nCRT neoadjuvant chemoradiotherapy, NAC neoadjuvant chemotherapy, pT pathological stage based on the tumor size and spread of cancer to nearby tissue, pN pathological stage based on spread of cancer to nearby lymph nodes, LCR lymphocyte count/C-reactive protein ratio. *P < 0.05
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