Table 1 Patient and procedural characteristics.

From: Osteopenia is associated with inferior survival in patients undergoing partial hepatectomy for hepatocellular carcinoma

Characteristics

All patients

Osteopenia

p value

n = 100

no n = 33

yes n = 67

 

Patient age (years)

67 ± 11

61 ± 14

70 ± 9

0.000

Patient BMI

26 ± 4

25 ± 4

26 ± 5

0.359

Patient sex ratio (F:M)

28:72

9:24

19:48

0.909

ASA

1

2

1 (3)

1 (2)

0.606

2

33

12 (36)

21 (31)

0.616

3

59

20 (61)

39 (58)

0.819

4

6

0 (0)

6 (9)

0.076

Preoperative labMELD

8 ± 3

8 ± 2

8 ± 3

0.180

Milan criteria

22

10 (30)

12 (18)

0.141

Cirrhosis

42

15 (46)

27 (40)

0.536

Preoperative AFP (µg/l)

2400 ± 9735

2787 ± 12,312

2141 ± 7787

0.263

Preoperative platelets (G/l)

247 ± 119

261 ± 144

238 ± 105

0.628

Preoperative AST (U/l)

54 ± 37

52 ± 40

55 ± 35

0.359

Preoperative ALT (U/l)

47 ± 46

56 ± 60

42 ± 33

0.601

Preoperative GGT (U/l)

170 ± 164

147 ± 145

180 ± 171

0.341

Preoperative albumin (g/l)

38 ± 10

37 ± 10

38 ± 9

0.680

SMI (cm2/m2)

45 ± 9

47 ± 9

45 ± 9

0.479

VFA (cm2)

174 ± 118

139 ± 90

191 ± 126

0.070

SFA (cm2)

188 ± 86

182 ± 88

191 ± 86

0.536

VSR

0.98 ± 0.67

0.85 ± 0.56

1.04 ± 0.73

0.273

BMD (HU)

153 ± 53

213 ± 40

123 ± 26

0.000

Preoperative therapie

PVE

6

0 (0)

6 (9)

0.076

Sorafenib

1

0 (0)

1 (2)

0.481

TACE

7

3 (9)

4 (6)

0.565

SIRT

3

0 (0)

3 (5)

0.217

Operative procedure

Atypical

24

11 (33)

13 (19)

0.125

Segmentectomy

20

5 (15)

15 (22)

0.395

Bisegementectomy

6

3 (9)

3 (5)

0.361

Hemihepatectomy

25

7 (21)

18 (27)

0.539

Extended resection

25

5 (15)

15 (22)

0.395

ALPPS resection

2

1 (3)

1 (2)

0.606

Other

3

1 (3)

2 (3)

0.990

Laparoscopic Procedure

21

8 (24)

13 (19)

0.524

Tumor Stage UICC

I

36

15 (46)

20 (30)

0.124

II

35

11(33)

24 (36)

0.806

IIIa

18

3 (9)

15 (22)

0.104

IIIb

5

0 (0)

5 (8)

0.107

IIIc

2

1 (3)

1 (2)

0.606

IVa

3

1 (3)

2 (3)

0.990

IVb

1

1 (3)

0 (0)

0.152

Largest Tumor Diameter (mm)

72 ± 41

65 ± 34

76 ± 44

0.289

Number of Tumors

1.9 ± 1.3

1.6 ± 1.3

2 ± 1.4

0.030

R0 Resection

85

28 (85)

57 (85)

0.746

  1. Values were given as mean ± standard deviation or absolute and relative frequencies (per cent). 1Refers to Clavien et al.26 3Refers to Slankamenac et al.27 4Refers to Staiger et al.29.
  2. BMI Body mass index; ASA American Society of Anesthesiologists; MELD model for end-stage liver disease; AFP alphafetoprotein; AST Aspartate aminotransferase; ALT Alanine aminotransferase; GGT Gamma glutamyltransferase; SMI Sceletal muscle index; VFA Visceral fat area; SFA Subcutanous fat area, VSR Visceral-to-subcutaneous fat ratio; BMD (HU) Bone mineral density (Hounsfield units); PVE Portal venous embolization; TACE Transarterial chemoembolization; SIRT Selective internal radiotherapy; UICC Union for International Cancer Control.
  3. Significant values are in bold.
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