Figure 1

Butyrate concentrations in the colon negatively correlate with serum Mg²⁺ levels in mice. (A–C) Simple linear regression analyses were performed on colonic SCFAs concentrations, obtained from a previously published dataset¹⁸, and serum Mg²⁺ levels of 25 wildtype male C57BL/6J mice. Simple linear regression analysis between colonic concentrations of butyrate (y = −2.24x + 1.52, r² = 0.22, P < 0.05) (A), acetate (y = −0.05x + 1.22, r² = 0.006) (B), propionate (y = 0.15x + 1.15, r² = 0.003) (C), and serum Mg²⁺ levels. Data is plotted as individual data points with the linear line indicating the relationship. P < 0.05 is considered significant.