Table 5 Multivariate Cox proportional risk analysis showing predictors of moderate COPD exacerbations (dependent variable).

From: Associations between serum mitokine levels and outcomes in stable COPD: an observational prospective study

Variable

B

p

HR

95% CI HR

Lower

Upper

Age (years)

0.029

0.054

1.029

1.000

1.059

Sex (female)

− 0.260

0.257

0.771

0.492

1.209

Current smoker

− 0.258

0.294

0.772

0.477

1.251

mMRC dyspnea score

0.088

0.494

1.092

0.849

1.403

Charlson index

− 0.060

0.475

0.942

0.799

1.110

FEV1 (%)

< 0.001

0.979

1.000

0.988

1.013

High risk of exacerbation

0.611

0.010

1.842

1.158

2.928

High HN levels

0.602

0.007

1.826

1.181

2.822

  1. High humanin levels = humanin higher than the median (> 246 pg/mL). High risk of exacerbation = 2 or more exacerbations during previous year or 1 previous admission. FEV1 = forced expiratory volume in the first second.
Back to article page