Table 2 Task-based functional connectivity differences for MVPA-derived seeds after 1-month on the low glutamate diet (2-back post-diet > 2-back baseline).

From: Low glutamate diet improves working memory and contributes to altering BOLD response and functional connectivity within working memory networks in Gulf War Illness

MVPA seed

Main region

Additional region(s)

MNI (X, Y, Z)

K

T (df = 23)

p-FDR

Cohen’s d

Network

Seed 1

L. Central Opercular Cortex

L. Planum Temporal

L. Heschl’s Gyrus

L. Parietal Operculum Cortex

L. Insular Cortex

L. Posterior Superior Temporal Gyrus

− 46 − 16 + 16

254

− 6.79

0.0002

2.83

 

R. Superior Temporal Gyrus

R. Heschl’s Gyrus

R. Planum Temporale

R. Putamen

R. Planum Polare

R. Insula

 + 60 − 24 + 06

235

− 6.86

0.0002

2.86

SM

L. Superior Temporal Gyrus

L. Temporal Pole

L. Frontal Orbital Cortex

L. Planum Polare

L. Frontal Operculum Cortex

L. Central Opercular Cortex

L. Insula

− 48 + 06 − 10

221

− 5.91

0.0002

2.46

SM

L. Putamen

L. Insular Cortex

L. Central Opercular Cortex

− 34 + 00 + 06

132

− 7.29

0.0051

3.04

VAN

L. Postcentral Gyrus

L. Anterior Supramarginal Gyrus

− 60 − 18 + 38

98

− 5.59

0.0181

2.33

VAN

L. Inferior Frontal Gyrus, pars opercularis

L. Central Opercular Cortex

L. Precentral Gyrus

L. Planum Polare

− 52 + 08 + 10

92

− 5.14

0.0199

2.14

VAN

Seed 2

L Angular Gyrus

L. Inferior parietal Lobule

− 38 − 72 + 44

160

5.33

0.0031

2.22

DMN

R. Cerebellum Crus I

R. Cerebellum Crus II

R. Lingual Gyrus

R. Lobule VI

 + 10 − 84 − 26

94

5.40

0.0358

2.25

FPN

R. Supplementary Motor Cortex

L. Superior Frontal Gyrus

R/L. Supplementary Motor Cortex

R/L. Precentral Gyrus

 + 02 − 14 + 68

523

− 6.59

 < 0.0001

2.75

SM

R. Superior Parietal Lobule

R. Postcentral Gyrus

 + 20 − 50 + 66

292

− 6.17

 < 0.0001

2.57

SM

L. Paracentral Lobule

R/L. Middle Cingulum

− 04 − 34 + 54

81

− 4.77

0.0484

1.98

SM

L. Precuneus

L. Superior Parietal Lobule

− 10 − 50 + 58

79

− 5.68

0.0484

2.36

VAN

  1. Network cortical and cerebellar networks from Yeo et al. (2011) and Buckner et al. (2011) 7-network parcellations, SC subcortical, SM somatomotor, VAN ventral attention network, DMN default mode network, FPN frontoparietal network.