Figure 1
From: Identification of mutations in SARS-CoV-2 PCR primer regions
Overview of PCR primer TRs and average rate of mutations along the length of the SARS-CoV-2 genome. (a) SARS-CoV-2 isolate Wuhan-Hu-1, complete genome (NCBI ID of the fasta sequence: NC_045512) showing genes coding proteins located in ORF1ab (including RdRp), spike protein (S), envelope protein (E), and nucleocapsid protein (N). (b) Number of TRs overlapping a genomic position across all investigated primer sets. (c) Estimated mutation rate of a genomic position in the CoVEO database. For details, see “Methods”. For the estimated mutation rate of different genomic positions in samples belonging to various variant strains, see Supplementary Fig. 2.
