Table 5 ICU characteristics survival.

From: Extreme obesity is a strong predictor for in-hospital mortality and the prevalence of long-COVID in severe COVID-19 patients with acute respiratory distress syndrome

 

Survivors

Range

Non-survivors

Range

p

n

90

 

94

  

Intubated at ICU admission

30 (33.3%)

 

21 (22.3%)

  

ARDS mild at ICU admission

7 (7.8%)

 

7 (7.4%)

  

ARDS moderate at ICU admission

41 (45.6%)

 

44 (46.8%)

  

ARDS severe at ICU admission

39 (43.3%)

 

43 (45.7%)

  

Septic shock at ICU admission

6 (6.7%)

 

18 (19.4%)

 

< 0.05

First Horovitz-index at ICU

112.5 (83; 165)

52.5–450

105 (75; 142.5)

45–262.5

 

Lowest Horovitz-index at ICU

75 (52.5; 90)

22.5–225

52.5 (45; 67.5)

22.5–135

 

Pmean at admission [mbar]

19 (16; 22)

7–28

20 (18; 22)

8–30

 

PEEP at admission [mbar]

13 (12; 15)

6–20

14 (12; 15)

6–20

 

pH at admission

7.40 (7.36; 7.46)

7.17–7.62

7.37 (7.31; 7.42)

6.81–7.59

 

PaCO2 at admission [kPa]

6.29 (5.38; 6.82)

3.23–9.86

6.64 (5.83; 7.52)

4.42–15.90

 

SpO2 at admission [%]

94 (91; 96)

56–100

93 (89; 96)

64–100

 

SOFA score at ICU admission

11 (8; 13)

5–16

12 (11; 14)

4–19

< 0.05

D-dimers at ICU admission [ng/ml]

4000 (1808; 7638)

484–20,000

6128 (4114; 10,994)

495–20,000

< 0.05

Lactate at ICU admission [mmol/L]

1.10 (0.85; 1.40)

0.40–3.30

1.30 (0.90; 1.90)

0.50–9.90

< 0.05

Duration mechanical ventilation ICU [days]

10 (6; 17)

2–56

13 (8; 17)

1–61

 

Reintubation

2 (2.2%)

 

2 (2.1%)

  

Prone position

48 (53.3%)

 

65 (69.1%)

 

< 0.05

Cycles of prone position

3 (2; 4)

1–14

4 (3; 7)

1–11

< 0.05

Tracheostomy

41 (45.6%)

 

41 (43.6%)

  

Days from intubation to Tracheostomy

13 (10; 15)

3–26

11 (8; 15

3–21

 

CRRT

15 (16.7%)

 

52 (55.3%)

 

< 0.05

Duration CRRT [hours}

337.01 (100.66; 483.67)

17.33–788.74

138.10 (30.17; 239.08)

1.44–906.53

< 0.05

ECMO

14 (15.6%)

 

35 (37.2%)

 

< 0.05

Duration ECMO [hours]

312.34 (208.30; 479.50)

70.78–1068.31

253.80 (163.27; 347.93)

16.78–577.63

 

Cytosorb

0

 

8 (8.5%)

 

< 0.05

Duration Cytosorb [hours]

  

20.00 (17.17; 21.15)

8.67–51.00

 

Red Cell Transfusion

5 (1; 8)

1–36

7 (3; 13)

1–40

 

NO inhalation

12 (13.3%)

 

50 (53.2%)

 

< 0.05

Corticosteroid

73 (81.1%)

 

92 (97.9%

 

< 0.05

Immunoglobulin

2 (2.2%)

 

2 (2.1%)

  

Convalescent plasma

20 (22.2%)

 

14 (14.9%)

  

Remdesivir

14 (15.6%)

 

6 (6.4%)

 

< 0.05

Anticoagulation

90 (100%)

 

94 (100%)

  

Argatroban at any time on ICU

8 (8.9%)

 

7 (7.4%)

 

< 0.05

UFH at any time on ICU

51 (56.7%)

 

89 (94.7%)

 

< 0.05

LMWH at any time on ICU

72 (80.0%)

 

43 (45.7%)

 

< 0.05

Bacteremia

36 (40.0%)

 

56 (59.6%)

 

< 0.05

Staph. aureus bacteremia

3 (3.3%)

 

9 (9.6%)

  

Catheter associated bacteremia

12 (13.3%)

 

12 (12.8%)

  

Antibiotics

84 (93.3%)

 

92 (97.9%)

  

Antimycotics

12 (13.3%)

 

16 (17.0%)

  

CRP maximum value [mg/l]

229.9 (144.4; 302.2)

31.4–584.7

305.5 (231.2; 373.5)

81.8–618.0

< 0.05

Interleukin 6 maximum value [pg/mL]

152.0 (80.5; 398.0)

8.6–21,728.0

674 (254; 2345)

15.9–792,732.0

< 0.05

Leucocytes maximum value [GPt/L]

17.19 (13.11; 22.43)

7.06–63.87

20.82 (16.75; 27.17)

3.14–63.64

< 0.05

Leucocytes minimum value [GPt/L]

7.22 (5.00; 9.39)

0.51–15.84

7.20 (4.63; 9.74)

0.20–22.47

 

Procalcitonin [ng/ml]

1.31 (0.43; 6.02)

0.09–373.20

7.39 (2.20; 15.60)

0.15–148.40

< 0.05

Prothrombin fragment F1 + 2 [pmol/l]

393 (231; 780)

98.0–4948

541 (339; 1001)

73–4948

 

Platelets maximum value [GPt/L]

355 (284; 461)

103–989

286 (219; 357)

48–617

< 0.05

Platelets minimum value [GPt/L]

170 (110; 219)

4–469

96 (47; 139)

1–414

< 0.05

  1. Data are median (Interquartile range) or n (%).
  2. Significant values are in [bold].
  3. ICU Intensive care unit, ARDS Acute respiratory distress syndrome, Pmean Mean pressure, PEEP Positive end-expiratory pressure, PaCO2 partial pressure of carbon dioxide, SpO2 Oxygen saturation, SOFA Sequential organ failure assessment, CRRT Continuous renal replacement therapy, NO Nitric oxide, UFH Unfractionated heparin, LMWH Low-molecular-weight heparin, Staph. Staphylococcus, CRP C-reactive protein, ECMO extracorporeal membrane oxygenation.