Table 7 Cox regressions for hospital mortality.

From: Extreme obesity is a strong predictor for in-hospital mortality and the prevalence of long-COVID in severe COVID-19 patients with acute respiratory distress syndrome

Variable

Bivariate regressions

Known at admission

Full model

HR

CI

HR

CI

HR

CI

n

184

 

184

 

184

 

Age

1.042**

1.020–1.064

1.051

1.023–1.080

1.092

1.053–1.132

Male

1.454

0.916–2.306

1.490

0.917–2.422

1.411

0.795–2.501

BMI: 35–40 kg/m2

0.884

0.492–1.586

1.178

0.630–2.206

1.922

0.961–3.843

BMI: > 40 kg/m2

1.084

0.499–2.353

1.718

0.715–4.128

3.380*

1.085–10.533

CCI

1.035

0.958–1.118

0.949

0.852–1.058

0.915

0.809–1.034

Septic shock at ICU admission

1.891*

1.145–3.121

1.258

0.728–2.174

1.692

0.906–3.161

SOFA score at ICU admission

1.125**

1.055–1.201

1.129**

1.037–1.230

1.084

0.957–1.227

D-Dimers at ICU admission: > 4000 ng/ml

1.524

0.997–2.331

1.621*

1.011–2.599

0.919

0.515–1.639

Logarithm of first Horovitz-index at ICU

0.901

0.580–1.399

0.949

0.573–1.571

1.369

0.741–2.530

Direct transfer to our ICU from other hospital

1.393

0.931–2.084

1.166

0.708–1.920

1.248

0.732–2.130

Intubated at ICU admission

1.652*

1.054–2.589

0.836

0.445–1.570

0.879

0.403–1.917

Time from first symptom to admission to our ICU

1.015

0.996–1.036

1.009

0.985–1.034

1.008

0.983–1.034

ECMO

1.542*

1.032–2.303

  

2.268*

1.193–4.311

CRRT

1.864**

1.274–2.726

  

1.216

0.684–2.162

NO inhalation

2.086**

1.425–3.055

  

2.434**

1.422–4.165

Prone position

1.071

0.714–1.605

  

1.108

0.641–1.917

PE

1.212

0.813–1.806

  

0.832

0.477–1.449

Pneumothorax

0.837

0.481–1.457

  

0.465

0.187–1.161

Lung emphysema

1.042

0.630–1.725

  

2.411

0.881–6.600

Mediastinal emphysema

1.009

0.534–1.904

  

0.896

0.247–3.247

Pleural effusion

1.215

0.830–1.776

  

0.915

0.561–1.492

Bacteremia

1.141

0.776–1.677

  

0.645

0.375–1.109

Logarithm of lowest Horovitz-index at ICU

0.357**

0.199–0.640

  

0.414*

0.189–0.907

Leucocytes maximum value: > 20 GPt/l

1.393

0.952–2.036

  

0.805

0.485–1.337

Interleukin 6 maximum value: > 150 pg/ml

2.272**

1.335–3.869

  

2.115

0.914–4.893

PCT maximum value: > 2 ng/ml

2.290**

1.462–3.588

  

1.832

0.938–3.577

CRP maximum value: > 400 mg/l

1.435

0.746–2.760

  

0.394

0.138–1.123

CRP maximum value: 200–400 mg/l

1.685

0.978–2.902

  

0.508

0.220–1.178

Platelets maximum value: > 350 GPt/l

0.488**

0.320–0.746

  

0.541*

0.302–0.969

Platelets minimum value: < 100 GPt/l

1.661**

1.135–2.430

  

0.921

0.512–1.657

Fusion in lung

1.383

0.767–2.494

  

0.871

0.430–1.766

Mycosis

1.079

0.714–1.631

  

1.071

0.626–1.832

Catheter associated bacteremia

0.753

0.439–1.291

  

0.703

0.354–1.397

Tracheostomy

0.660*

0.449–0.970

  

0.402**

0.243–0.664

DVT

1.184

0.796–1.760

  

1.253

0.730–2.152

  1. Hazard ratios with 95%-confidence intervals for hospital mortality from bivariate Cox regression, Cox regression including covariates known at admission and Cox regression including all covariates (full model) (significance levels: * = 5%, ** = 1%).
  2. BMI Body-Mass-Index, CCI Charlson ComorbidityIndex, CI Confidence interval, CRP C-reactive protein, CRRT Continuous renal replacement therapy, DVT Deep vein thrombosis, ECMO extracorporeal membrane oxygenation, HR Hazard ration, ICU Intensive care unit, NO Nitric oxide, PCT Procalcitonin, PE Pulmonary embolism.
Back to article page