Table 1 Listing of the top 25 treatments for the AD portrait, the female AD portrait, and the male AD portrait.

From: Alzheimer’s disease large-scale gene expression portrait identifies exercise as the top theoretical treatment

Rank	GEO #	AD portrait		GEO #	Female AD		GEO #	Male AD
Rank	GEO #	Treatment	Score	GEO #	Treatment	Score	GEO #	Treatment	Score
1	GSE110298	Exercise	121.46	GSE110298	Exercise	122.13	GSE110298	Exercise	81.63
2	11 Datasets	Exercise c*	68.70	GSE110298	Exercise	70.44	GSE33137	Curcumin	55.71
3	GSE110298	Exercise	63.05	11 Datasets	Exercise c*	70.06	11 datasets	Exercise c*	49.67
4	GSE84185	Fluoxetine	50.84	GSE10748	D-serine	52.07	GSE110298	Exercise	40.86
5	GSE33137	Curcumin	46.17	GSE10748	D-serine	51.46	GSE85936	Cocaine	37.49
6	GSE104338	Safflower oil	42.86	GSE27532	Desipramine	46.66	GSE84185	Fluoxetine	37.21
7	GSE27532	Desipramine	42.81	GSE104338	Safflower oil	40.77	GSE27532	Desipramine	35.84
8	GSE10748	D-serine	40.57	GSE84185	Fluoxetine	38.56	GSE10748	D-serine	25.55
9	GSE10748	D-serine	40.27	GSE33137	Curcumin	35.89	GSE74677	Chlorpyrifos	23.62
10	GSE84185	Fluoxetine	32.96	GSE7955	Permethrin	33.28	GSE10748	D-serine	23.03
11	GSE7955	Permethrin	31.24	13 Datasets	Fluoxetine c*	31.17	GSE104338	Safflower oil	22.37
12	GSE84185	Fluoxetine	28.62	GSE84185	Fluoxetine	31.09	13 Datasets	Fluoxetine c*	22.02
13	13 Datasets	Fluoxetine c*	27.14	GSE29075	Exercise	27.85	GSE84185	Fluoxetine	20.49
14	GSE29075	Exercise	26.77	GSE99349	Cocaine	23.13	GSE7955	Deltamethrin	20.11
15	GSE99349	Cocaine	25.93	GSE10748	D-serine	21.37	GSE7955	Permethrin	19.53
16	GSE85936	Cocaine	25.13	GSE84185	Fluoxetine	19.85	GSE99349	Cocaine	18.57
17	GSE64607	Exercise	24.95	GSE43748	Amphet.	19.76	GSE84185	Fluoxetine	18.50
18	GSE43748	Amphet.	24.49	GSE84185	Fluoxetine	18.69	GSE29075	Exercise	17.54
19	GSE74677	Chlorpyrifos	23.89	GSE7955	Deltamethrin	18.41	GSE64607	Exercise	17.29
20	GSE84185	Fluoxetine	22.25	GSE74677	Chlorpyrifos	18.21	GSE27532	Desipramine	16.63
21	GSE88736	Cocaine	20.89	GSE27532	Desipramine	17.68	GSE88736	Cocaine	15.82
22	GSE7955	Deltamethrin	20.82	GSE46717	Methamph.	16.70	GSE67755	Haloperidol	15.58
23	GSE10748	D-serine	18.06	GSE88736	Cocaine	16.58	GSE39980	Zonisamide	14.93
24	GSE81672	Imipramine	17.46	GSE64607	Exercise	16.50	GSE117758	Dexameth.	14.93
25	GSE27532	Desipramine	16.52	GSE9798	Corticost.	16.47	GSE81672	Imipramine	14.40

Additional details, including species, sex, and tissue source are provided in Supplementary Table S2.
c* composite, corticost. Corticosterone, amphet. amphetamine, methamph. methamphetamine, dexameth. dexamethasone.

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Table 1 Listing of the top 25 treatments for the AD portrait, the female AD portrait, and the male AD portrait.

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