Figure 3
Raman spectra of cancer biofluids contain distinct features that can be attributed to the metabolites identified by GC-MS to drive diagnostic model performance. For each biofluid, average spectra of the cancer samples were fit with their respective metabolites. The average plasma cluster for cancer patients (blue) was fit with the reference spectra below for valine (green), histidine (magenta), tryptophan (yellow), 9-myristoleate (orange), and malonic acid (rose). The average saliva cluster for cancer patients (blue) was fit with the reference spectra below for trans-4-hydroxyproline (green), propane-1,3-diol (magenta), 3-phosphoglycerate (yellow), 1-monopalmitin (orange), and azelaic acid (rose).
