Table 1 Clinical characteristics of patients and controls.

From: Association between iron status and incident coronary artery disease: a population based-cohort study

 

Male

Female

Control (n = 381)

CAD (n = 349)

P

Control (n = 262)

CAD (n = 294)

P

Age (years)

56.05 ± 10.75

58.56 ± 10.82

0.052

58.45 ± 9.93

60.55 ± 9.36

0.060

BMI (kg/m2)

22.99 ± 2.46

24.23 ± 2.55

0.095

23.08 ± 2.21

24.18 ± 2.68

0.008

SBP (mmHg)

120.32 ± 9.28

127.92 ± 17.07

 < 0.001

120.66 ± 9.5

130.68 ± 16.93

 < 0.001

DBP (mmHg)

74.84 ± 9.04

78.76 ± 11.14

 < 0.001

74.24 ± 8.90

78.45 ± 11.5

 < 0.001

HR (heart ratio)

70.21 ± 5.08

77.45 ± 10.47

 < 0.001

70.63 ± 4.83

77.66 ± 10.22

 < 0.001

Smoking status (%)

60 (15.75)

118 (33.81)

 < 0.001

29 (11.07)

31 (10.54)

0.842

Drinker (%)

56 (14.7)

101 (28.94)

 < 0.001

27 (10.31)

24 (8.16)

0.382

HbA1C (%)

5.4 ± 0.45

6.09 ± 1.21

 < 0.001

5.52 ± 0.53

6.29 ± 1.36

 < 0.001

FPG (mmol/L)

5.06 ± 0.6

5.33 ± 1.79

 < 0.001

5.11 ± 0.78

5.58 ± 1.88

 < 0.001

ALT(U/L)

24.31 ± 17.02

42.57 ± 125.79

0.021

18.5 ± 10.7

42.54 ± 236.76

0.303

AST(U/L)

22.22 ± 11.71

32.17 ± 38.03

 < 0.001

21.67 ± 8.56

57.01 ± 437.43

0.416

TBIL (µmol/L)

12.99 ± 5.27

12.19 ± 8.66

0.345

10.23 ± 4.13

9.72 ± 5.49

0.395

BILD (µmol/L)

5.53 ± 1.85

5.4 ± 4.34

0.828

4.62 ± 1.63

4.75 ± 2.69

0.590

GGT(U/L)

30.31 ± 18.19

32.89 ± 27.75

0.206

23.05 ± 20.92

26.23 ± 18.86

0.172

TP(g/L)

72.86 ± 4.09

65.46 ± 5.41

 < 0.001

74.09 ± 4.03

67.02 ± 5.58

 < 0.001

ALB(g/L)

47.32 ± 2.82

40.94 ± 4.02

 < 0.001

46.79 ± 2.47

41.31 ± 4.18

 < 0.001

ALP(U/L)

68.85 ± 14.57

71.29 ± 20.42

0.056

77.92 ± 22.81

77.06 ± 25.41

0.768

TC (mmol/L)

4.64 ± 0.99

3.41 ± 0.88

 < 0.001

4.82 ± 1

3.9 ± 1.08

 < 0.001

TG (mmol/L)

1.74 ± 1.07

1.49 ± 1.03

0.094

1.44 ± 0.77

1.58 ± 1.25

0.403

HDL-C (mmol/L)

1.2 ± 0.29

0.99 ± 0.24

 < 0.001

1.39 ± 0.29

1.13 ± 0.31

 < 0.001

LDL-C (mmol/L)

2.91 ± 0.87

1.95 ± 0.79

 < 0.001

2.95 ± 0.92

2.23 ± 0.89

 < 0.001

APOA (g/L)

1.37 ± 0.26

1.11 ± 0.26

 < 0.001

1.40 ± 0.24

1.17 ± 0.26

0.003

APOB (g/L)

0.86 ± 0.27

0.84 ± 0.36

0.727

0.86 ± 0.22

0.84 ± 0.37

0.525

Lpa (g/L)

0.16 ± 0.17

0.33 ± 1.78

0.404

0.16 ± 0.18

0.24 ± 0.26

0.042

homocysteine (umol/L)

13.59 ± 9.17

15.58 ± 9.08

0.01

12.15 ± 7.05

15.89 ± 8.56

 < 0.001

hsCRP (mg/L)

1.61 ± 1.61

5.68 ± 14.05

0.002

1.57 ± 0.83

8.88 ± 26.34

0.010

CREA (μmol/L)

80.77 ± 12.4

87.44 ± 81.8

0.183

65.44 ± 14.7

67.46 ± 24.14

0.438

Urea (mmol/L)

5.1 ± 1.23

6 ± 3.24

 < 0.001

4.9 ± 1.23

5.37 ± 1.98

0.007

UA (mmol/L)

365.08 ± 89.14

319.21 ± 100.07

 < 0.001

278.9 ± 72.51

284.58 ± 96.06

0.601

eGFR

94.17 ± 13.18

90.39 ± 18.27

0.008

92.36 ± 14.45

89.97 ± 19.15

0.267

IRON (µmol/L)

23.35 ± 8.46

14.14 ± 6.4

0.001

18.10 ± 5.46

13.42 ± 5.77

 < 0.001

Ferritin (ng/mL)

206.22 ± 191.69

274.03 ± 191.58

 < 0.001

111.89 ± 81.45

233.5 ± 178.27

 < 0.001

UIBC (µmol/L)

34.57 ± 9.99

34.38 ± 7.57

0.804

35.43 ± 6.3

34.09 ± 7.17

0.108

TIBC (µmol/L)

57.14 ± 8.13

48.52 ± 8.9

 < 0.001

53.58 ± 5.36

47.51 ± 8.47

 < 0.001

Tfs (transferrin saturation, %)

41.15 ± 14.23

28.7 ± 11.33

0.009

32.02 ± 9.99

27.89 ± 10.30

0 < 0.001

Iron deficiency

 

64 (18.33%)

  

75 (25.5)

0.028

  1. SBP systolic blood pressure, DBP diastolic blood pressure, BMI body mass index, ALT alanine aminotransferase, AST aspartate aminotransferase, TC total cholesterol, TG triglyceride, HDL-c high density lipoprotein-c, LDL-c low density lipoprotein-c, ApoA Apolipoprotein A, ApoB Apolipoprotein B, FBG fasting blood glucose, HbA1c glycosylated hemoglobin, hs-CRP high sensitive C-reactive protein.
  2. Significant values are in bold.
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