Table 1 Cox regression analysis of factors linked with OS in PAAD, both univariate and multivariate.
Characteristics | Total (N) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | ||
RAB7A | 178 | 2.089 (1.209–3.611) | 0.008 | 1.746 (1.027–2.970) | 0.040 |
Radiation therapy | 163 | ||||
No | 118 | Reference | |||
Yes | 45 | 0.508 (0.298–0.866) | 0.013 | 0.452 (0.252–0.809) | 0.008 |
Histologic grade | 176 | ||||
G1&G2 | 126 | Reference | |||
G3&G4 | 50 | 1.538 (0.996–2.376) | 0.052 | 1.935 (1.194–3.135) | 0.007 |
Residual tumor | 164 | ||||
R0 | 107 | Reference | |||
R1&R2 | 57 | 1.645 (1.056–2.561) | 0.028 | 2.050 (1.272–3.304) | 0.003 |
Pathologic stage | 175 | ||||
Stage I&Stage II | 167 | Reference | |||
Stage III&Stage IV | 8 | 0.673 (0.212–2.135) | 0.501 | ||
Gender | 178 | ||||
Female | 80 | Reference | |||
Male | 98 | 0.809 (0.537–1.219) | 0.311 | ||
Smoker | 144 | ||||
No | 65 | Reference | |||
Yes | 79 | 1.086 (0.687–1.719) | 0.724 | ||
Alcohol history | 166 | ||||
No | 65 | Reference | |||
Yes | 101 | 1.147 (0.738–1.783) | 0.542 | ||
Age | 178 | ||||
< = 65 | 93 | Reference | |||
> 65 | 85 | 1.290 (0.854–1.948) | 0.227 | ||
History of diabetes | 146 | ||||
No | 108 | Reference | |||
Yes | 38 | 0.927 (0.532–1.615) | 0.790 | ||
History of chronic pancreatitis | 141 | ||||
No | 128 | Reference | |||
Yes | 13 | 1.177 (0.562–2.464) | 0.666 | ||
Family history of cancer | 110 | ||||
No | 47 | Reference | |||
Yes | 63 | 1.117 (0.650–1.920) | 0.689 | ||
