Table 1 Multi comparison (post hoc Tukey analysis) of mtDNA copy number, telomere length, PGC1a, PGC1b and CDKN2A between patient and controls in brain tissues.

From: Mitochondrial biogenesis, telomere length and cellular senescence in Parkinson’s disease and Lewy body dementia

Condition	Condition	Mean diff	SE	t ratio	Adj. p value	Lower 95	Upper 95
*mtDNA* copy number
Control	PD	3584.95	1732.17	2.07	0.177	105.79	7064.12
Control	PDD	7471.8	1980.2	3.77	0.002	3494.46	11,449.16
Control	DLB	9246.82	1498.03	6.17	< 0.001	6237.92	12,255.73
PD	PDD	3886.85	1962.35	1.98	0.208	− 54.64	7828.35
PD	DLB	5661.87	1754.23	3.23	0.011	2138.39	9185.35
PDD	DLB	1775.01	2012.81	0.88	0.382	− 2267.84	5817.87
Telomere length
Control	PD	− 0.22	0.125	− 1.76	0.303	− 0.473	0.032
Control	PDD	− 0.322	0.136	− 2.37	0.097	− 0.596	− 0.048
Control	DLB	− 0.514	0.101	− 5.06	< 0.001	− 0.718	− 0.309
PD	PDD	− 0.101	0.131	− 0.77	0.866	− 0.365	0.162
PD	DLB	− 0.293	0.124	− 2.35	0.100	− 0.544	− 0.042
PDD	DLB	− 0.191	0.135	− 1.42	0.496	− 0.464	0.08
PGC1 α
Control	PD	0.463	0.257	1.8	0.282	− 0.05	0.976
Control	PDD	− 0.053	0.213	− 0.25	0.994	− 0.479	0.372
Control	DLB	0.007	0.206	0.04	0.999	− 0.405	0.420
PD	PDD	− 0.516	0.226	− 2.28	0.113	− 0.969	− 0.063
PD	DLB	− 0.455	0.234	− 1.94	0.221	− 0.924	0.013
PDD	DLB	0.060	0.186	0.33	0.987	− 0.311	0.432
PGC − 1β
Control	PD	0.531	0.182	2.91	0.024	0.166	0.895
Control	PDD	0.395	0.149	2.65	0.048	0.097	0.694
Control	DLB	0.355	0.147	2.41	0.085	0.060	0.649
PD	PDD	− 0.135	0.161	− 0.84	0.835	− 0.457	0.186
PD	DLB	− 0.176	0.166	− 1.06	0.717	− 0.509	0.156
PDD	DLB	− 0.040	0.130	− 0.31	0.989	− 0.300	0.219
CDKN2A
Control	PD	− 0.041	0.373	− 0.11	0.999	− 0.786	0.702
Control	PDD	0.057	0.318	0.18	0.997	− 0.577	0.692
Control	DLB	− 1.012	0.301	− 3.36	0.006	− 1.613	− 0.411
PD	PDD	0.099	0.327	0.30	0.990	− 0.554	0.752
PD	DLB	− 0.970	0.330	− 2.94	0.022	− 1.630	− 0.311
PDD	DLB	− 1.069	0.269	− 3.97	0.001	− 1.607	− 0.532

Significant are in value [bold].

Back to article page

Table 1 Multi comparison (post hoc Tukey analysis) of mtDNA copy number, telomere length, PGC1a, PGC1b and CDKN2A between patient and controls in brain tissues.

Search

Quick links