Figure 6 | Scientific Reports

Figure 6

From: Enhanced CHOLESTEROL biosynthesis promotes breast cancer metastasis via modulating CCDC25 expression and neutrophil extracellular traps formation

Figure 6

Inhibition of cholesterol biosynthesis reduces CCDC25 expression in lung metastases. (a) Images showed representative immunostaining for CCDC25 (red), H3cit (green) and DAPI (blue) in the lung metastases of indicated mice as in Fig. 4. Scale bar: 50 µm. (b) Images showed representative immunostaining for CCDC25, Caveolin-1 and DAPI in the lung metastases of indicated mice. Scale bar: 50 µm. Relative immunofluorescence scores were calculated and statistically analyzed. *P < 0.05; ** P < 0.01;*** P < 0.001.

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