Table 1 Baseline and disease characteristics.
From: Plasma proteomic characterization of the development of acute kidney injury in early sepsis patients
No AKI (n = 19) (median ± IQR) or n (%) | AKI (n = 17) (median ± IQR) or n (%) | |
|---|---|---|
Age (years) | 65 (59–75) | 60 (52–76) |
Sex (male) | 12 (63%) | 13 (76%) |
History of chronic kidney disease | 6 (32%) | 7 (41%) |
History of cardiovascular disease | 13 (68%) | 10 (59%) |
History of diabetes mellitus | 9 (47%) | 7 (41%) |
Infection focus: airways/pneumonia | 6 (32%) | 5 (29%) |
Infection focus: urogenital | 9 (47%) | 7 (41%) |
Infection focus: abdominal | 2 (11%) | 3 (18%) |
Infection focus: unknown | 2 (11%) | 2 (12%) |
Systolic blood pressure (mmHg) | 132 (125–150) | 105 (90–130)* |
Diastolic blood pressure (mmHg) | 70 (65–80) | 66 (52–80) |
Mean arterial pressure (mmHg) | 93 (88–107) | 78 (67–97) |
Heart frequency (bpm) | 110 (95–120) | 110 (100–125) |
Respiratory frequency (per minute) | 22 (18–28) | 20 (18–29) |
Oxygen saturation (%) | 94 (91–98) | 95 (90–97) |
Glasgow coma score | 15 (15–15) | 15 (15–15) |
Body temperature (°C) | 38.5 (38.2–38.8) | 38.6 (38.0–39.4) |
Haemoglobin (mmol/L) | 7.1 (6. 1–8.1) | 7.2 (6.1–8.6) |
Leukocytes (106/mL) | 12.2 (10–15.3) | 8.5 (5–15.6) |
Bandemia (> 5%) | 2 (11%) | 1 (6%) |
Thrombocytes (109/mL) | 205 (174–317) | 189 (146–217) |
CRP (mg/L) | 63 (22–197) | 146 (80–335) |
Lactate (mmol/L) | 1.5 (1.1–1.7) | 1.7 (1.2–2.1) |
Multiple organ failure | 3 (16%) | 3 (18%) |
Liver failure | 0 (0%) | 0 (0%) |
Respiratory failure | 6 (32%) | 3 (18%) |
ICU admittance | 1 (5%) | 3 (18%) |
Length-of-stay in hospital (days) | 6 (2–8) | 8 (5–14) |
Deceased in hospital | 1 (5%) | 1 (6%) |
Oncology | 2 (11%) | 6 (35%) |
Nefrotoxic drugs (i.e. cytostatics) | 2 (11%) | 5 (29%) |
