Table 2 Course of renal function.
From: Plasma proteomic characterization of the development of acute kidney injury in early sepsis patients
| Ā | No AKI (nā=ā19) (medianā±āIQR) or n (%) | AKI (nā=ā17) (medianā±āIQR) or n (%) |
|---|---|---|
Baseline creatinine (μmol/L) | 77 (62ā102) | 96 (84ā132) |
Baseline urea (mmol/L) | 6 (5.3ā8.4) | 7.5 (6ā10.0) |
Baseline eGFR (ml/min/1.73m2) | 90.7 (53.6ā103.9) | 68.4 (46.1ā80.3) |
CKD class: 1 (>ā90) | 10 (53%) | 3 (18%) |
CKD class: 2 (60ā90) | 4 (21%) | 7 (41%) |
CKD class: 3a (45ā60) | 1 (5%) | 1 (6%) |
CKD class: 3b (30ā45) | 0 (0%) | 0 (0%) |
CKD class: 4 (15ā30) | 3 (16%) | 3 (18%) |
CKD class: 5 (<ā15) | 1 (5%) | 3 (18%) |
Creatinine upon admission (μmol/L) | 81 (65ā105) | 160 (104ā222)** |
eGFR upon admission (ml/min/1.73Ā m2) | 80.9 (49.5ā95.3) | 40.3 (29.3ā53.6)** |
Urea/creatinine ratio at admission | 90.2 (72.7ā108.9) | 76.4 (53.8ā102.6) |
Urea upon admission (mmol/L) | 7.4 (5.5ā10.3) | 11.7 (8.9ā16.5)* |
Maximum creatinineā<ā48Ā h (μmol/L) | 87 (66ā105) | 176 (118ā222)** |
Creatinine at discharge (μmol/L) | 65 (57ā90) | 103 (77ā134) |
eGFR at discharge (ml/min/1.73m2) | 88.3 (59.1ā127.5) | 69.6 (46.1ā98.4) |
Urea at discharge (mmol/L) | 5.3 (3.7ā8.6) | 7.6 (6.8ā9.4) |
AKI at discharge | 0 (0%) | 1 (6%) |
Creatinine after discharge (μmol/L) | 65 (57ā90) | 103 (77ā134) |
eGFR after discharge (ml/min/1.73Ā m2) | 88.3 (59.1ā127.5) | 69.6 (46.1ā98.4) |