Table 1 DEGs in the shared signature in IL-17 signaling pathway.

UCTR

CCL11

C–C motif chemokine ligand 11

3.31E−08

1.19E−07

CCL2

C–C motif chemokine ligand 2

9.95E−24

3.17E−22

CCL20

C–C motif chemokine ligand 20

9.24E−13

5.72E−12

CCL22

C–C motif chemokine ligand 22

3.89E−15

3.25E−14

CD70

CD70 molecule

8.64E−27

5.08E−25

CEBPB

CCAAT enhancer binding protein beta

3.11E−20

5.41E−19

CLCF1

Cardiotrophin like cytokine factor 1

1.37E−16

4.56E−26

CXCL1

C-X-C motif chemokine ligand 1

4.65E−45

3.35E−41

CXCL3

C-X-C motif chemokine ligand 3

7.67E−34

3.76E−36

DEFB1

Defensin beta 1

2.16E−15

1.87E−14

EDA

Ectodysplasin A

2.33E−05

1.54E−23

FOS

Fos proto-oncogene, AP-1 transcription factor subunit

5.36E−14

3.93E−13

IL11

Interleukin 11

2.12E−16

2.13E−15

IL33

Interleukin 33

7.31E−25

3.42E−24

IL1A

Interleukin 1 alpha

1.84E−25

8.22E−24

IL1B

Interleukin 1 beta

6.48E−24

2.18E−22

LCN2

Lipocalin 2

2.94E−26

1.54E−24

LTA

Lymphotoxin alpha

8.59E−17

9.16E−16

LTB

Lymphotoxin beta

2.68E−15

2.29E−14

MAPK11

Mitogen-activated protein kinase 11

1.65E−31

3.13E−29

MMP2

Matrix metallopeptidase 2

9.15E−09

5.53E−10

MMP3

Matrix metallopeptidase 3

4.15E−24

1.46E−22

MMP9

Matrix metallopeptidase 9

5.06E−10

5.32E−19

MRAS

Muscle RAS oncogene homolog

1.95E−22

9.68E−23

MUC5AC

Mucin 5AC, oligomeric mucusgel-forming

2.1E−16

1.32E−16

NOS2

Nitric oxide synthase 2

3.03E−10

3.87E−22

OSM

Oncostatin M

1.32E−17

1.57E−16

PGF

Placental growth factor

6.05E−21

1.19E−19

PIK3CD

Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta

4.57E−14

3.38E−13

PTGS2

Prostaglandin-endoperoxide synthase 2

6.59E−17

7.14E−16

RGS16

Regulator of G protein signaling 16

5.13E−26

2.54E−24

TGFB2

Transforming growth factor beta 2

6.29E−21

1.24E−19

TGFB3

Transforming growth factor beta 3

4.34E−10

1.54E−16

TNF

Tumor necrosis factor

2.58E−13

1.72E−12

TNFRSF11B

TNF receptor superfamily member 11b

1.24E−11

6.62E−11

TNFSF8

TNF superfamily member 8

1.9E−20

3.44E−19

TNFSF9

TNF superfamily member 9

3.63E−30

4.63E−28

TNFSF11

TNF superfamily member 11

8.88E−14

6.31E−13

TNFSF13B

TNF superfamily member 13b

2.43E−17

2.8E−16

VEGFC

Vascular endothelial growth factor C

1.01E−35

6.63E−33

PSTR

CDC25A

Cell division cycle 25A

2.54E−03

2.55E−24

IL7R

Interleukin 7 receptor

2.78E−04

5.18E−23

LYN

LYN proto-oncogene, Src family tyrosine kinase

2.40E−44

1.60E−52

SHC1

SHC adaptor protein 1

3.99E−12

8.00E−38

SLC2A1

Solute carrier family 2 member 1

2.63E−34

6.02E−33

STAT1

Signal transducer and activator of transcription 1

3.29E−03

1.93E−56