Table 2 Cytokine expression.

From: Cytokines help suggest aplastic anemia with pulmonary bacterial or co-fungal infection

Parameter

A: no infection

B: bacterial infection

C: fungal and bacterial infection

P (A VS B)

P (A VS C)

P (B VS C)

IL-4 (pg/ml)

2.72 (1.82–3.95)

2.84 (1.80–5.00)

3.55 (2.08–6.67)

0.3332

0.0170

0.1406

IL-5 (pg/ml)

2.15 (1.59–2.98)

2.29 (1.71–3.64)

2.19 (1.45–3.71)

0.1389

0.8949

0.4078

IL-6 (pg/ml)

8.19 (6.10–10.41)

26.43 (17.40–37.48)

104.73 (75.80–260.86)

0.0000

0.0000

0.0000

IL-8 (pg/ml)

14.13 (6.75–35.46)

26.62 (14.19–60.58)

103.15 (46.06–209.31)

0.0001

0.0000

0.0000

IL-10 (pg/ml)

4.38 (3.3–6.44)

4.96 (3.95–8.20)

7.08 (4.18–15.61)

0.0062

0.0000

0.0075

IL-12p70 (pg/ml)

3.94 (3.27–5.71)

4.29 (3.44–6.52)

5.80 (4.32–6.83)

0.0741

0.0196

0.0167

IL-1β (pg/ml)

1.64 (1.16–2.16)

1.75 (1.41–2.32)

1.93 (1.38–2.45)

0.1343

0.0001

0.1668

IL-2 (pg/ml)

3.08 (2.23–4.80)

3.49 (2.60–5.28)

4.44 (3.04–6.03)

0.0910

0.0087

0.0949

IFN-γ (pg/ml)

2.87 (1.89–3.82)

3.07 (2.43–4.10)

3.56 (2.10–4.56)

0.0244

0.0742

0.8305

TNF-α (pg/ml)

2.84 (2.02–3.93)

3.07 (2.05–4.42)

3.17 (2.42–4.36)

0.4348

0.1165

0.2170

TNF-β (pg/ml)

3.16 (2.57–3.90)

3.20 (2.66–3.75)

3.73 (2.99–4.09)

0.8191

0.0258

0.0324

IL-17A (pg/ml)

2.29 (1.37–3.33)

2.69 (1.59–4.23)

3.40 (1.93–4.69)

0.0321

0.0023

0.1358

IL-17F (pg/ml)

3.36 (2.47–4.67)

4.23 (13.06–6.50)

3.99 (2.48–5.69)

0.0005

0.0642

0.2383

IL-22 (pg/ml)

1.01 (0.58–1.80)

1.24 (0.62–2.59)

1.39 (0.92–1.98)

0.1850

0.0392

0.1514

  1. The difference in the expression of cytokines between the patient’s lungs with bacterial infection and without infection was detected by the Mann–Whitney U test.
  2. P < 0.05 means there is a statistical difference.