Figure 1

Illustration of the statistical methodology demonstrated on the example of gait velocity during preferred walking speed in m/s. Using a binary logistic regression (BLR) model, the distribution of the logistic curve-fit is depicted on the left-hand side (A) with 1 for NPH and 0 for being healthy. The corresponding receiver operating characteristic (ROC) curve is shown on the right-hand side (B). The determined gait parameter threshold (A) as well as the optimal operating point of the ROC curve (B) with balanced true positive rate (sensitivity) and false positive rate (1-specificity) are marked with a red circle.