Table 4 Characteristics of patients 2 months after hospital discharge from COVID-19 stratified by absolute recovery and non-recovery from ALI. Group comparisons (recovery vs non-recovery) of categorical variables were performed using the Chi-squared test. Group comparison of continuous variables in means and standard deviations (sd) were performed using the Wilcoxon test. A p-value < 0.05t was considered statistically significant.
Not recovered | Recovered | p value | |
|---|---|---|---|
N (%) | 130 (18.8%) | 562 (81.2%) | |
Demographics | |||
Age in years, mean (sd) | 55.2 ± 16.9 | 61.4 ± 15.9 | < 0.001 |
Female gender, n (%) | 40 (30.8%) | 254 (45.2%) | 0.003 |
Race/ethnicity, n (%) | |||
Black/African American | 29 (22.3%) | 204 (36.3%) | 0.007 |
White | 9 (6.9%) | 37 (6.6%) | 0.77 |
Other | 19 (14.6%) | 76 (13.5%) | 0.02 |
Hispanic | 73 (56.2%) | 245 (43.6%) | 0.01 |
Comorbidities, n (%) | |||
Hypertension | 42 (32.3%) | 256 (45.6%) | 0.008 |
Diabetes | 45 (34.6%) | 262 (46.6%) | 0.02 |
Congestive heart failure | 6 (4.6%) | 26 (4.6%) | 0.99 |
COPD | 13 (10%) | 76 (13.5%) | 0.34 |
Coronary artery disease | 8 (6.2%) | 54 (9.6%) | 0.28 |
Chronic kidney disease | 45 (34.6%) | 262 (46.6%) | 0.02 |
Obesity | 21 (16.2%) | 109 (19.4%) | 0.47 |
Invasive mechanical ventilation | 1 (0.8%) | 2 (0.4%) | 0.99 |
ICU | 23 (17.7%) | 85 (15.1%) | 0.55 |
Steroid | 63 (48.5%) | 279 (49.6%) | 0.88 |
Remdesivir | 25 (19.2%) | 111 (19.8%) | 0.99 |
Return lab values, mean (sd) | |||
Alkaline phosphatase, IU/L | 139.99 (113.52) | 97.87 (51.74) | < 0.001 |
Alanine aminotransferase, U/L | 122.48 (358.23) | 22.54 (9.28) | < 0.001 |
Aspartate aminotransferase, U/L | 105.44 (378.71) | 25.24 (14.14) | < 0.001 |
Bilirubin, mg/dL | 0.77 (0.71) | 0.6 (0.49) | 0.002 |
Brain natriuretic peptide (pg/mL) | 1543.93 (3495.06) | 666.54 (2158.73) | 0.09 |
Creatinine, mg/dL | 1.35 (1.56) | 1.54 (1.72) | 0.29 |
C-reactive protein, mg/dL | 10.15 (11.08) | 4.75 (8.25) | 0.01 |
d-dimer, µg/mL | 3.45 (4.95) | 1.93 (3.72) | 0.11 |
Ferritin, ng/mL | 721.83 (1379.59) | 361.3 (430.63) | 0.03 |
Lactate dehydrogenase, U/L | 404.58 (418.27) | 305.59 (174.64) | 0.13 |
Lymphocytes, (%) | 24.91 (14.64) | 27.54 (12.62) | 0.05 |
Prothrombin time, s | 15.38 (3.63) | 15.24 (7.62) | 0.9 |
Systolic blood pressure, mmHg | 129.82 (23.61) | 135.19 (22.76) | 0.03 |
Troponin-T, ng/mL | 0.07 (0.18) | 0.06 (0.42) | 0.83 |
White blood cell count (k/µL) | 9.08 (5.65) | 8.01 (3.53) | 0.01 |
