Table 3 Association between maternal pre-pregnancy body mass index and offspring hyperactivity-inattention symptoms (SDQ score ≥ 7) in ELFE (n = 10,898) and EPIPAGE 2 (n = 2646) at 5.5 years.

From: Maternal pre-pregnancy obesity and offspring hyperactivity-inattention symptoms at 5 years in preterm and term children: a multi-cohort analysis

Variable

Unadjusted OR [95%CI]

p-value

Adjusted ORa [95%CI]

p-value

ELFE

Obese (≥ 30 kg/m2)

1.42 [1.19, 1.69]

 < 0.001

1.27 [1.06, 1.53]

0.01

Overweight (25-30 kg/m2)

1.28 [1.10, 1.49]

 < 0.01

1.16 [1.00, 1.36]

0.05

Normal (18.5-25 kg/m2)

REF

 

REF

 

Underweight (< 18.5 kg/m2)

1.27 [1.03, 1.56]

0.03

1.14 [0.92, 1.41]

0.24

EPIPAGE 2

Obese (≥ 30 kg/m2)

1.39 [1.02, 1.89]

0.03

1.48 [1.06, 2.08]

0.02

Overweight (25-30 kg/m2)

0.91 [0.68, 1.20]

0.50

0.96 [0.72, 1.30]

0.81

Normal (18.5-25 kg/m2)

REF

 

REF

 

Underweight (< 18.5 kg/m2)

1.29 [0.83, 2.02]

0.26

1.07 [0.69, 1.67]

0.75

  1. aAdjusted for maternal age at birth, maternal education, household income (ELFE), household socioeconomic category (EPIPAGE 2), parity, sex, psychological problems during pregnancy (ELFE), anxiety symptoms (EPIPAGE 2), singleton pregnancy (EPIPAGE 2), maternal physical activity during pregnancy (ELFE), maternal healthy diet score during pregnancy (ELFE), maternal alcohol intake during pregnancy (ELFE), maternal smoking during pregnancy, child age at evaluation, gestational age, breastfeeding, cause of prematurity (EPIPAGE 2), childcare at 2 years, screentime at 2 years (ELFE), HOME score (EPIPAGE 2), difficulties falling asleep at 2 years (ELFE) and frequent night waking at 2 years (EPIPAGE 2).
  2. Missing covariates are imputed and weighted using IPW.
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