Table 3 Diagnostic performance of each approach for predicting advanced fibrosis in cohort with a 3.7% prevalence of advanced fibrosis.

91.2 ± 10.7

(71.4 to 100.0)

43.7 ± 3.7

(36.6 to 50.8)

5.8 ± 0.7

(4.2 to 7.1)

99.2 ± 0.9

(97.2 to 100.0)

–

-

84.4 ± 13.7

(57.1 to 100.0)

73.5 ± 3.3

(67.2 to 79.8)

11.0 ± 2.0

(6.9 to 14.9)

99.2 ± 0.7

(97.7 to 100.0)

28.7 ± 3.2

(22.6 to 34.7)

57.6 ± 3.6

(50.5 to 64.7)

81.5 ± 14.7

(57.1 to 100.0)

79.0 ± 3.0

(73.2 to 84.7)

13.1 ± 2.7

(7.8 to 18.4)

99.1 ± 0.7

(97.7 to 100.0)

23.2 ± 2.9

(17.4 to 28.9)

40.0 ± 3.5

(33.2 to 46.8)

 − 2.9 ± 6.3

(− 14.3 to 0.0)

5.5 ± 1.7

(2.7 to 8.8)

2.1 ± 1.3

(− 0.6 to 4.7)

 − 0.1 ± 0.3

(− 0.7 to 0.2)

 − 5.4 ± 1.6

(− 8.9 to − 2.6)

 − 17.7 ± 2.8

(− 23.2 to − 12.6)

83.4 ± 14.0

(57.1 to 100.0)

78.4 ± 3.1

(72.1 to 84.2)

13.1 ± 2.6

(8.0 to 18.2)

99.2 ± 0.7

(97.8 to 100.0)

23.8 ± 3.0

(17.9 to 30.0)

36.3 ± 3.4

(29.5 to 43.2)

 − 1.0 ± 3.7

(− 14.3 to 0.0)

5.0 ± 1.6

(2.2 to 8.2)

2.1 ± 1.0

(− 0.1 to 4.3)

0.0 ± 0.2

(− 0.7 to 0.2)

 − 4.8 ± 1.5

(− 7.9 to − 2.1)

 − 21.3 ± 3.0

(− 27.3 to − 15.8)