Table 1 Dataset description.

From: Mapping human disease-associated enzymes into Reactome allows characterization of disease groups and their interactions

Set

Enzymes

Diseases *

Associations

Reactome annotations ^

Reactome Roots °

Biunivocal enzyme to disease relations

744

744

744

805 (1167; 2798)

27

Univocal enzyme to disease relations

87

61

87

212 (424; 513)

20

Non univocal enzyme to disease relations

663

1793

2277

949 (1304; 3845)

27

Total

1494

2539

3108

1165 (1528; 5570)

27

  1. * The same disease can appear in more than one list, ^ the same Reactome term can appear in more than one list; values between brackets indicate the expanded Reactome list from leaves to roots and the reaction numbers (in italic), respectively; ° the same Reactome root can appear in more than one list.
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