Figure 3

Evaluation and validation of the risk model in TCGA and ICGC cohort. (A) The risk curve is based on the risk score of each sample in the TCGA database (top). The scatterplot is based on the survival status of each sample (bottom). The bright and red dots represent low-risk group/survival and high-risk group/death, respectively. (B) Kaplan–Meier curves for comparison of the OS between low- and high-risk groups. (C) ROC curves demonstrated the predictive efficiency of the risk score. (D) Heatmap demonstrating the distribution of the six pyroptosis and inflammasome-related gene expressions in the TCGA cohort. (E) The risk curve is based on the risk score of each sample in the ICGC database (top). The scatterplot is based on the survival status of each sample (bottom). The bright and red dots represent low-risk group/survival and high-risk group/death, respectively. (F) Kaplan–Meier curves for comparison of the OS between low- and high-risk groups. (G) Time-dependent ROC curves for PDACs. (H) The heatmap displayed the expression levels of pyroptosis and inflammasome-related genes in the high-risk and low-risk groups.