Figure 2 | Scientific Reports

Figure 2

From: Placental vascular alterations are associated with early neurodevelopmental and pulmonary impairment in the rabbit fetal growth restriction model

Figure 2

Brain assessment in postnatal day 1 rabbits. (A) Neurobehavioral tests (left) and grouped scores (right) from 43 FGR and 61 control subjects from 16 litters. (B) Neuron density was assessed in cresyl violet stained slides in the depicted areas (top images). Bottom images show neuron density in the frontal cortex of FGR and control brains. To the right, neuron density from 27 FGR and 29 control subjects from 16 litters. (C) Representative images of apoptosis (TUNEL), and astrogliosis (GFAP) in hippocampus and corpus callosum, respectively. Data from 14 FGR and 19 control subjects from 11 litters. CA1 cornu ammonis 1, CA3 cornu ammonis 3, DG dentate gyrus, AVTN anteroventral thalamic nuclei. Data were analysed using a linear mixed-effects model and displayed as mean ± SD with significance as *0.05 ≥ p > 0.01; **0.01 ≥ p > 0.001.; ***0.001 > p > 0.0001; ****p < 0.0001.

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