Table 2 Characteristics of enrolled normal pregnant women and patients with ICP grouped by gestational age.

Age, median (range), years

30, (27; 33)

30, (27; 33)

ns

29, (27; 32)

30, (28; 34)

ns

ns

ns

TP, (g/L)

64, (63; 67)

63, (60; 65)

0.004

64.4, (61.8; 66.73)

62.4, (59.78; 64.58)

0.024

ns

ns

ALB, (g/L)

37, (35; 38)

36, (35; 37)

ns

35.2, (33.65; 36.75)

33.85, (32.2; 35.15)

0.001

0.001

 < 0.001

ALT, median (range), U/L

12, (10; 17)

18, (11; 29)

0.012

12.5, (10; 17)

14.5, (11; 32.5)

0.003

ns

ns

TB, median (range), μmol/L

5.6, (4.45; 7.55)

7.5, (5.55; 9.1)

0.032

6.2, (4.98; 8.05)

6.2, (5.08; 9.85)

ns

ns

ns

DB, median (range), μmol/L

2.4, (1.7; 2.95)

2.8, (2.05; 3.85)

0.026

2.4, (2.1; 3.23)

2.6, (2.18; 4.23)

0.017

ns

ns

IB, median (range), μmol/L

3.4, (2.8; 4.25)

4.5, (3; 5.75)

0.048

3.75, (2.8; 4.55)

3.55, (2.78; 5.1)

ns

ns

ns

TBA, median (range), μmol/L

2, (1; 3)

13, (11; 21.5)

 < 0.001

2, (2; 3)

13, (10.75; 15.25)

 < 0.001

ns

0.029

CR, median (range), μmol/L

43, (38.25; 47.25)

48.15, (42.48; 51.68)

0.001

45.6, (42.3; 49.85)

53.9, (48.4; 64.95)

 < 0.001

0.010

 < 0.001

UREA, median (range), mmol/L

2.49, (2.14; 2.81)

2.65, (2.14; 2.93)

ns

2.44, (1.97; 2.93)

2.87, (2.33; 3.45)

0.011

ns

0.035

URIC, median (range), μmol/L

225, (205.5; 253.5)

215, (187; 238)

ns

255, (222; 300)

288, (233; 345.5)

ns

0.001

 < 0.001

TG, median (range), mmol/L

2.15, (1.67; 2.76)

2.08, (1.65; 2.60)

ns

3.09, (2.44; 3.72)

3.07, (2.36; 4.22)

ns

 < 0.001

 < 0.001

TCH, median (range), mmol/L

5.94, (5.46; 6.63)

5.9, (5.05; 6.38)

ns

6.7, (5.79; 7.22)

6.29, (5.5; 7.3)

ns

0.011

0.016

HDL, median (range), mmol/L

1.73, (1.58; 1.93)

1.86, (1.6; 2.05)

ns

1.7, (1.55; 1.94)

1.57, (1.39; 1.98)

ns

ns

0.029

GLU, median (range), mmol/L

4.39, (4.19; 4.52)

4.29, (4.06; 4.55)

ns

4.37, (4.20; 4.53)

4.35, (4.18; 4.65)

ns

ns

ns