Figure 1

Representative HRCT images of patients with SSc-ILD. Axial (A) and coronal (B) HRCT images of an anti-CCP antibody-negative patient with SSc-ILD. They show extensive ground-glass opacities and traction bronchiectasis with basal predominance. These findings are typical of a non-specific interstitial pneumonia pattern. Axial (C) and coronal (D) HRCT images of an anti-CCP antibody-positive patient with SSc-ILD. They show predominant lower lobe pulmonary fibrosis and traction bronchiectasis with exuberant honeycombing sign. These findings are consistent with the usual interstitial pneumonia pattern. HRCT: high resolution computed tomography; SSc: systemic sclerosis; ILD: interstitial lung disease.