Table 2 Relationship between anti-CCP antibody/RF and interstitial lung disease in connective tissue diseases.

From: A retrospective analysis of the relationship between anti-cyclic citrullinated peptide antibody and interstitial lung disease in systemic sclerosis

 

ILD with anti-CCP/RF negative

ILD with RF single positive

ILD with anti-CCP positive

p value

SLE

31/588 (5.3%)

28/262 (10.7%)

14/86 (16.3%)

< 0.001

PM/DM

41/105 (39.0%)

18/33 (54.5%)

7/18 (38.9%)

0.843

SSc

49/151 (32.5%)

41/67 (61.2%)

27/42 (64.3%)

< 0.001

  1. Bold text indicates statistical significance. Values are expressed as n (%). all p values Bonferroni corrected.
  2. SLE, systemic lupus erythematous; PM, polymyositis; DM, dermatomyositis; SSc, systemic sclerosis; ILD, interstitial lung disease.