Table 3 Associations between miliary and PFS.
cHR (95% CI) | p value | aHR (95% CI) | p value | |
|---|---|---|---|---|
Age (ref = < 65) | 0.94 (0.68, 1.29) | 0.687 | 0.80 (0.56, 1.14) | 0.209 |
Gender (ref = female) | 0.94 (0.68, 1.29) | 0.685 | 0.80 (0.52, 1.22) | 0.296 |
Smoking (ref = no) | 1.12 (0.77, 1.64) | 0.556 | 1.18 (0.70, 1.97) | 0.535 |
PS (ECOG) (ref = 0–1) | 2.30 (1.66, 3.20) | < 0.001* | 2.33 (1.61, 3.37) | < 0.001* |
Bone metastasis (ref = no) | 1.27 (0.94, 1.72) | 0.126 | 0.97 (0.68, 1.38) | 0.869 |
Brain metastasis (ref = no) | 1.47 (1.06, 2.04) | 0.020* | 1.41 (0.99, 2.02) | 0.058 |
Liver metastasis (ref = no) | 1.96 (1.29, 2.99) | 0.002* | 2.22 (1.40, 3.53) | 0.001* |
EGFR (ref = 19 deletion) | 1.34 (0.98, 1.82) | 0.064 | 1.25 (0.90, 1.75) | 0.187 |
TKI (ref = 1st generation) | 0.68 (0.49, 0.93) | 0.015* | 0.59 (0.42, 0.83) | 0.003* |
Miliary (ref = no) | 1.47 (1.05, 2.05) | 0.025* | 1.11 (0.75, 1.63) | 0.612 |
